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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Pablo Santos | 0.433 | 2043 | |
| 2 | Juan Garay | 0.476 | 2032 | |
| 3 | Jose Robles# | 0.562 | 2050 | |
| 4 | Rafael Olmedo | 0.690 | 2030 | |
| 5 | Joel Londono# | 0.808 | 2045 | |
| 6 | Tony Soto | 0.911 | 2029 | |
| 7 | Jorge Dimond | 1.096 | 2045 | |
| 8 | Raul Pazos | 1.115 | 2041 | |
| 9 | Jose Zorrilla | 1.156 | 2029 | |
| 10 | Victor Silva# | 1.180 | 2050 | |
| 11 | Mario Molina# | 1.232 | 2036 | |
| 12 | Joe Ritchie | 1.251 | 2035 | |
| 13 | Greg Denne | 1.252 | 2032 | |
| 14 | Jose Castro# | 1.280 | 2047 | |
| 15 | Javier de la Cruz# | 1.321 | 2050 | |
| 16 | Hector Osuna# | 1.362 | 2045 | |
| 17 | Gabriel Pena# | 1.371 | 2050 | |
| 18 | Willie Silva | 1.398 | 2044 | |
| 19 | Leonardo Crawford | 1.414 | 2015 | |
| 20 | Carlos Juarez# | 1.449 | 2048 | |
| 21 | Tommy Santos# | 1.463 | 2046 | |
| 22 | John Olsen | 1.473 | 2030 | |
| 23 | Tomas Ramirez# | 1.475 | 2050 | |
| 24 | Jose Cruz# | 1.495 | 2047 | |
| 25 | Dedgar Jimenez | 1.500 | 2013 | |
| 25 | Ruben Ramos# | 1.500 | 2046 | |
| 27 | Marcos Diplan | 1.539 | 2014 | |
| 27 | Mario Molina# | 1.539 | 2037 | |
| 29 | Aaron Slegers | 1.540 | 2022 | |
| 30 | Josh Atkinson | 1.546 | 2030 | |
| 31 | Matt Gomes | 1.561 | 2034 | |
| 32 | Mike Heintzelman | 1.606 | 2034 | |
| 33 | Jordan Alarcon# | 1.629 | 2047 | |
| 34 | Emanuel Barruncho | 1.633 | 2043 | |
| 35 | Joe Allen | 1.636 | 2030 | |
| 36 | Humberto Mejia | 1.688 | 2015 | |
| 36 | Yonatan Quintin | 1.688 | 2016 | |
| 38 | Nate Karns | 1.695 | 2021 | |
| 38 | Marcos Diplan | 1.695 | 2016 | |
| 40 | Freddie Poe# | 1.699 | 2032 | |
| 41 | Lachlan Wells | 1.706 | 2024 | |
| 42 | Alex Juarez | 1.709 | 2025 | |
| 43 | Jesus Fleites | 1.719 | 2045 | |
| 43 | Victor Reyes# | 1.719 | 2049 | |
| 45 | Carlos Arranaga | 1.730 | 2026 | |
| 46 | Dave Mendoza# | 1.751 | 2050 | |
| 47 | Graham Lawson | 1.761 | 2018 | |
| 48 | Jose Uribe | 1.767 | 2042 | |
| 49 | Andrew Cantu | 1.769 | 2032 | |
| 50 | Joe Allen | 1.776 | 2031 | |
| 51 | Mario Orona# | 1.784 | 2045 | |
| 51 | Chandler Walker | 1.784 | 2038 | |
| 53 | Joel Aguilar | 1.792 | 2045 | |
| 54 | Drew Rucinski | 1.793 | 2020 | |
| 54 | Willie Zapien | 1.793 | 2031 | |
| 56 | Victor Salinas# | 1.809 | 2050 | |
| 57 | Shun Ito# | 1.814 | 2044 | |
| 58 | Jonathon Littleton | 1.829 | 2033 | |
| 59 | Matt Gomes | 1.849 | 2033 | |
| 60 | Luis Galindo | 1.853 | 2043 | |
| 60 | Michel Monaco | 1.853 | 2045 | |
| 62 | Leo Rodriguez | 1.859 | 2031 | |
| 62 | Michael Lorenzen | 1.859 | 2024 | |
| 64 | Manny Amzalak | 1.866 | 2021 | |
| 65 | Estevan Becerril# | 1.871 | 2049 | |
| 66 | Will Sanchez | 1.876 | 2045 | |
| 67 | Arturo Brignoni | 1.878 | 2029 | |
| 68 | Chris Carrillo# | 1.887 | 2050 | |
| 69 | Adam Dinerman | 1.889 | 2035 | |
| 70 | Kelly Smeulders# | 1.901 | 2044 | |
| 71 | Freddy Castellanos | 1.921 | 2043 | |
| 72 | Jerry Cancel# | 1.929 | 2045 | |
| 72 | Marco Mendez | 1.929 | 2043 | |
| 72 | Angel Cordova# | 1.929 | 2050 | |
| 75 | Jose Mancillas | 1.955 | 2045 | |
| 76 | Roberto Cevallos | 1.962 | 2044 | |
| 76 | Ivan Vasquez* | 1.962 | 2030 | |
| 78 | Giulio Martinez | 1.964 | 2044 | |
| 79 | Jose Torres# | 1.966 | 2042 | |
| 80 | Alex Arellano | 1.973 | 2045 | |
| 81 | Juan Ceballos# | 1.976 | 2045 | |
| 82 | Chris Villar# | 1.978 | 2049 | |
| 83 | Jerry Pagan | 1.987 | 2045 | |
| 83 | Armando Leon | 1.987 | 2034 | |
| 85 | Leon Nunez | 1.989 | 2045 | |
| 86 | Alex Cadena | 2.000 | 2042 | |
| 87 | Ramiro Esquivel# | 2.013 | 2042 | |
| 88 | David Rogel | 2.020 | 2043 | |
| 89 | Tony Cingrani | 2.030 | 2024 | |
| 90 | Francisco Gomez | 2.031 | 2043 | |
| 91 | Juan Escobedo# | 2.043 | 2050 | |
| 91 | Yoshifumi Yamashiro# | 2.043 | 2049 | |
| 93 | Gillian Wernet | 2.044 | 2016 | |
| 94 | Alfredo Merida | 2.047 | 2045 | |
| 95 | Dylan Warren | 2.049 | 2039 | |
| 96 | Sandy Baez | 2.054 | 2013 | |
| 97 | Steve Barcellos# | 2.058 | 2038 | |
| 97 | Victor Sanchez | 2.058 | 2032 | |
| 99 | Javy Batista# | 2.069 | 2045 | |
| 100 | Willie Garcia# | 2.077 | 2050 |
