| # | Name | Team | Opp | Date | Score | IP | R | H | HR | BB | K | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brad Jorgensen | LV | SF | June 13, 2106 | 2-0 | 11.1 | 0 | 1 | 0 | 2 | 15 | 117 |
| 2 | Brian Hamblin | TB | BAL | May 7, 2106 | 10-0 | 9.0 | 0 | 2 | 0 | 1 | 14 | 102 |
| 3 | Greg Earle | LV | LAD | Sept. 17, 2106 | 5-0 | 9.0 | 0 | 2 | 0 | 1 | 11 | 99 |
| 4 | Curtis Moore | CIN | PHI | Aug. 9, 2106 | 9-0 | 9.0 | 0 | 1 | 0 | 0 | 7 | 99 |
| 5 | Andy Bourdeau | ATL | LAD | June 16, 2106 | 1-0 | 9.0 | 0 | 1 | 0 | 1 | 8 | 98 |
| 6 | Russ Einhorn | PIT | MIL | Sept. 25, 2106 | 7-0 | 8.0 | 0 | 1 | 0 | 0 | 12 | 98 |
| 7 | Pedro Sandoval | LV | CLE | April 10, 2106 | 6-0 | 8.2 | 0 | 2 | 0 | 2 | 12 | 96 |
| 8 | Emilio Rios | NYM | CIN | Aug. 6, 2106 | 5-0 | 9.0 | 0 | 1 | 0 | 1 | 6 | 96 |
| 9 | Danny Solis | MIN | DET | April 29, 2106 | 4-0 | 9.0 | 0 | 1 | 0 | 1 | 6 | 96 |
| 10 | Billy Benedict | LAD | SD | May 15, 2106 | 4-1 | 9.0 | 1 | 2 | 0 | 0 | 8 | 95 |
| 11 | Tim Titolo | CWS | KC | July 19, 2106 | 5-0 | 9.0 | 0 | 4 | 0 | 0 | 9 | 95 |
| 12 | Brad Jorgensen | LV | ARI | July 11, 2106 | 1-0 | 8.0 | 0 | 2 | 0 | 0 | 11 | 95 |
| 13 | Jim Bush | LV | ARI | July 10, 2106 | 5-0 | 8.2 | 0 | 2 | 0 | 1 | 8 | 94 |
| 14 | Jeff Lee | COL | CHC | May 9, 2106 | 9-0 | 9.0 | 0 | 3 | 0 | 1 | 8 | 94 |
| 15 | Nick Laramie | ATL | LV | May 3, 2106 | 9-1 | 9.0 | 1 | 2 | 0 | 1 | 9 | 94 |
| 16 | Andy Bourdeau | ATL | COL | May 20, 2106 | 14-0 | 9.0 | 0 | 3 | 0 | 1 | 8 | 94 |
| 17 | Bill McEnerney | STL | SD | July 11, 2106 | 3-0 | 8.0 | 0 | 2 | 0 | 0 | 10 | 94 |
| 18 | Cory Tillotson | STL | MIN | June 23, 2106 | 3-0 | 9.0 | 0 | 1 | 0 | 1 | 4 | 94 |
| 19 | Bill Fike | KC | HOU | June 5, 2106 | 3-0 | 9.0 | 0 | 0 | 0 | 2 | 4 | 94 |
| 20 | Danny Torres | CWS | TEX | July 27, 2106 | 10-0 | 9.0 | 0 | 4 | 0 | 0 | 7 | 93 |
| 21 | Bobby Judd | SF | CHC | June 15, 2106 | 3-1 | 8.1 | 1 | 1 | 0 | 1 | 10 | 93 |
| 22 | Bobby Judd | SF | MIN | April 10, 2106 | 4-0 | 8.1 | 0 | 3 | 0 | 0 | 9 | 93 |
| 23 | Nick Palmer | WAS | NYM | Sept. 29, 2106 | 5-0 | 9.0 | 0 | 4 | 0 | 0 | 6 | 92 |
| 24 | Wally Sharp | SEA | OAK | Sept. 14, 2106 | 2-0 | 8.0 | 0 | 2 | 0 | 1 | 10 | 92 |
| 25 | Darius Shaheed | STL | COL | Sept. 1, 2106 | 6-0 | 8.1 | 0 | 1 | 0 | 1 | 6 | 92 |
| 26 | Kihachi Okuhara | HOU | KC | April 24, 2106 | 1-0 | 9.0 | 0 | 2 | 0 | 2 | 5 | 91 |
| 27 | Dustin Walker | LV | LAD | Sept. 26, 2106 | 4-0 | 8.2 | 0 | 4 | 0 | 0 | 7 | 91 |
| 28 | Michael Watson | CIN | MIL | May 11, 2106 | 7-0 | 7.2 | 0 | 3 | 0 | 1 | 13 | 91 |
| 29 | Dustin Walker | LV | ARI | May 14, 2106 | 4-0 | 7.2 | 0 | 1 | 0 | 1 | 9 | 91 |
| 30 | Dustin Walker | LV | PHI | May 31, 2106 | 3-0 | 8.0 | 0 | 1 | 0 | 1 | 7 | 91 |