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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aaron O'Day | 2020-2020 | 8 | 8 | .500 | 3.37 | 24 | 24 | 0 | 0 | 0 | 133.1 | 119 | 50 | 7 | 51 | 107 |
| John O'Day | 2014-2014 | 5 | 8 | .385 | 5.05 | 20 | 20 | 0 | 0 | 0 | 117.2 | 138 | 66 | 10 | 39 | 104 |
| Quentin O'Dell | 2024-2024 | 0 | 0 | .000 | 2.35 | 2 | 0 | 0 | 0 | 1 | 7.2 | 4 | 2 | 0 | 2 | 6 |
| Bryan O'Halloran | 2023-2023 | 4 | 4 | .500 | 4.78 | 10 | 10 | 0 | 0 | 0 | 49.0 | 52 | 26 | 5 | 26 | 39 |
| Dan O'Keefe | 2024-2024 | 0 | 1 | .000 | 1.93 | 2 | 2 | 0 | 0 | 0 | 9.1 | 9 | 2 | 1 | 6 | 12 |
| Will O'Neal | 2022-2023 | 16 | 19 | .457 | 3.63 | 59 | 59 | 0 | 0 | 0 | 304.2 | 323 | 123 | 25 | 59 | 195 |
| Sean O'Sullivan | 2012-2012 | 0 | 1 | .000 | 2.11 | 3 | 3 | 0 | 0 | 0 | 21.1 | 22 | 5 | 0 | 4 | 13 |
| Brett Oberholtzer | 2012-2012 | 1 | 1 | .500 | 3.07 | 3 | 2 | 0 | 0 | 0 | 14.2 | 10 | 5 | 2 | 4 | 15 |
| Roy Offerman | 2020-2024 | 19 | 1 | .950 | 2.36 | 49 | 10 | 2 | 1 | 2 | 183.0 | 128 | 48 | 12 | 46 | 151 |
| Jason Olbryc | 2020-2022 | 6 | 1 | .857 | 3.80 | 22 | 1 | 0 | 0 | 1 | 47.1 | 53 | 20 | 3 | 16 | 42 |
| José Olivo | 2016-2018 | 5 | 3 | .625 | 5.40 | 67 | 0 | 0 | 0 | 2 | 110.0 | 113 | 66 | 6 | 72 | 103 |
| Juan Oramas | 2012-2012 | 0 | 0 | .000 | 2.35 | 1 | 1 | 0 | 0 | 0 | 7.2 | 4 | 2 | 1 | 1 | 6 |
| Lawrence Ortíz | 2021-2021 | 1 | 1 | .500 | 2.57 | 22 | 0 | 0 | 0 | 1 | 21.0 | 20 | 6 | 1 | 11 | 19 |
| Pedro Ortíz | 2018-2023 | 13 | 7 | .650 | 3.80 | 120 | 7 | 0 | 0 | 4 | 265.0 | 249 | 112 | 16 | 118 | 276 |
| Victor Ortíz | 2016-2016 | 0 | 2 | .000 | 4.85 | 12 | 0 | 0 | 0 | 0 | 13.0 | 6 | 7 | 2 | 11 | 14 |
| Roberto Osuna | 2014-2014 | 7 | 6 | .538 | 4.86 | 21 | 21 | 0 | 0 | 0 | 109.1 | 122 | 59 | 8 | 45 | 111 |
| Pancho Otero | 2023-2024 | 4 | 6 | .400 | 4.12 | 34 | 13 | 0 | 0 | 3 | 111.1 | 107 | 51 | 11 | 37 | 118 |
| Teo Ottenhof | 2015-2018 | 7 | 10 | .412 | 4.31 | 90 | 0 | 0 | 0 | 47 | 94.0 | 89 | 45 | 10 | 56 | 134 |
| Bryan Owen | 2019-2020 | 2 | 9 | .182 | 4.55 | 22 | 22 | 0 | 0 | 0 | 112.2 | 112 | 57 | 13 | 41 | 90 |
| Richard Owens | 2013-2013 | 4 | 3 | .571 | 2.83 | 11 | 11 | 0 | 0 | 0 | 63.2 | 61 | 20 | 2 | 27 | 54 |
