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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Fred O'Bryan | 2019-2020 | .278 | 5 | 55 | 0 | 0 | 0 | 0.00 | 0 |
| Shane O'Connor | 2020-2022 | .359 | 1 | 4 | 0 | 0 | 0 | 0.00 | 0 |
| Aaron O'Day | 2018-2018 | .000 | 0 | 0 | 0 | 2 | 0 | 4.79 | 19 |
| John O'Day | 2012-2013 | .148 | 1 | 7 | 1 | 10 | 0 | 6.10 | 98 |
| Duncan O'Dell | 2018-2019 | .311 | 4 | 24 | 0 | 0 | 0 | 0.00 | 0 |
| Bryan O'Halloran | 2020-2021 | .000 | 0 | 0 | 4 | 5 | 3 | 5.51 | 70 |
| Trent O'Hannon | 2013-2014 | .249 | 7 | 53 | 0 | 0 | 0 | 0.00 | 0 |
| John O'Herlihy | 2018-2019 | .223 | 6 | 40 | 0 | 0 | 0 | 0.00 | 0 |
| Neal O'Neill | 2021-2023 | .272 | 5 | 39 | 0 | 0 | 0 | 0.00 | 0 |
| Chris O'Reilly | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 2.57 | 8 |
| Sam O'Reilly | 2021-2021 | .288 | 7 | 40 | 0 | 0 | 0 | 0.00 | 0 |
| Steven O'Toole | 2019-2019 | .289 | 5 | 20 | 0 | 0 | 0 | 0.00 | 0 |
| Ted Obregon | 2012-2012 | .406 | 4 | 21 | 0 | 0 | 0 | 0.00 | 0 |
| Jesús Ochoa | 2020-2020 | .250 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Manuel Ochoa | 2017-2019 | .286 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Dwayne Ockey | 2019-2019 | .000 | 0 | 0 | 0 | 0 | 0 | 11.57 | 3 |
| Tadanobu Ogawa | 2012-2012 | .588 | 5 | 18 | 0 | 0 | 0 | 0.00 | 0 |
| Sotan Ohayashi | 2013-2013 | .209 | 0 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Pedro Okuda | 2012-2012 | .278 | 0 | 10 | 0 | 0 | 0 | 0.00 | 0 |
| Jefferson Olacio | 2015-2015 | .000 | 0 | 0 | 0 | 0 | 1 | 0.00 | 3 |
| Jason Olbryc | 2019-2021 | .000 | 0 | 0 | 0 | 0 | 1 | 5.14 | 11 |
| José Olivo | 2016-2018 | .000 | 0 | 0 | 3 | 11 | 1 | 6.24 | 103 |
| Whit Olmstead | 2015-2016 | .284 | 20 | 75 | 0 | 0 | 0 | 0.00 | 0 |
| Pedro Ordiales | 2016-2016 | .250 | 2 | 14 | 0 | 0 | 0 | 0.00 | 0 |
| Cody Orgeron | 2019-2019 | .254 | 4 | 15 | 0 | 0 | 0 | 0.00 | 0 |
| Derek Orndorff | 2022-2023 | .320 | 0 | 4 | 0 | 0 | 0 | 0.00 | 0 |
| Cristóbal Orozco | 2022-2023 | .000 | 0 | 0 | 2 | 1 | 1 | 5.86 | 22 |
| Alfredo Ortega | 2021-2023 | .225 | 2 | 26 | 0 | 0 | 0 | 0.00 | 0 |
| Cristo Ortega | 2020-2020 | .262 | 0 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| José Ortega | 2018-2018 | .000 | 0 | 0 | 1 | 1 | 0 | 7.41 | 17 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| JeanPierre Ortiz | 2022-2023 | .223 | 4 | 36 | 0 | 0 | 0 | 0.00 | 0 |
| Joseph Ortiz | 2020-2021 | .230 | 4 | 22 | 0 | 0 | 0 | 0.00 | 0 |
| Bartolo Ortíz | 2022-2022 | .282 | 2 | 26 | 0 | 0 | 0 | 0.00 | 0 |
| José Ortíz | 2018-2021 | .227 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Lawrence Ortíz | 2016-2016 | .000 | 0 | 0 | 2 | 0 | 1 | 1.74 | 11 |
| Manuel Ortíz | 2019-2019 | .174 | 1 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| Paolo Ortíz | 2016-2016 | .500 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Tony Ortíz | 2023-2023 | .143 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Bubba Osborn | 2017-2018 | .269 | 6 | 50 | 0 | 0 | 0 | 0.00 | 0 |
| J.R. Osmond | 2023-2023 | .253 | 0 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| Kyle Ostrowski | 2020-2020 | .000 | 0 | 0 | 1 | 2 | 0 | 3.73 | 34 |
| Tyson Oswalt | 2017-2017 | .000 | 0 | 0 | 4 | 4 | 0 | 4.66 | 87 |
| Miguel Otero | 2016-2017 | .269 | 6 | 61 | 0 | 0 | 0 | 0.00 | 0 |
| Matt Ow-Yang | 2021-2021 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 6 |
| Bryan Owen | 2019-2019 | .269 | 1 | 2 | 1 | 0 | 0 | 1.42 | 15 |
| Jared Owens | 2023-2023 | .198 | 3 | 21 | 0 | 0 | 0 | 0.00 | 0 |
| Channing O’Donnell | 2023-2023 | .000 | 0 | 0 | 3 | 3 | 0 | 5.72 | 57 |
