| # | Name | Team | Opp | Date | Score | AB | H | RBI | HR | R | BB | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Joey Block | STL | NYY | June 8, 2043 | 12-9 | 4 | 4 | 6 | 2 | 3 | 1 | 110 |
| 2 | Danny Nelson | MIA | MIL | July 13, 2043 | 13-8 | 4 | 3 | 7 | 2 | 3 | 1 | 105 |
| 3 | Juan Arreola | ATL | SF | May 29, 2043 | 11-0 | 5 | 5 | 5 | 1 | 3 | 0 | 101 |
| 4 | Ismael Barajas | NYM | PHI | May 5, 2043 | 11-13 | 3 | 3 | 4 | 2 | 4 | 2 | 100 |
| 5 | Luis Pimentel | SD | CIN | June 16, 2043 | 11-1 | 4 | 3 | 5 | 3 | 3 | 1 | 96 |
| 6 | Mike Wright | TB | TEX | April 20, 2043 | 18-12 | 5 | 5 | 4 | 0 | 4 | 0 | 96 |
| 7 | Luis Luna | OAK | TEX | June 23, 2043 | 10-2 | 5 | 3 | 8 | 2 | 2 | 0 | 96 |
| 8 | Nate Reynolds | DET | CLE | April 8, 2043 | 15-1 | 5 | 4 | 8 | 1 | 1 | 0 | 96 |
| 9 | Adan Levandoski | TOR | MIA | June 23, 2043 | 9-4 | 5 | 4 | 5 | 2 | 3 | 0 | 94 |
| 10 | Mike Boothe | KC | TEX | May 19, 2043 | 9-2 | 5 | 4 | 6 | 2 | 2 | 0 | 94 |
| 11 | Eric Castro | TOR | NYY | July 13, 2043 | 18-6 | 5 | 4 | 5 | 1 | 3 | 1 | 94 |
| 12 | Jaquan Brown | OAK | MIA | June 5, 2043 | 9-1 | 4 | 3 | 6 | 2 | 3 | 0 | 93 |
| 13 | Glaucio Riis | SEA | KC | June 23, 2043 | 12-6 | 3 | 3 | 5 | 2 | 2 | 2 | 93 |
| 14 | Luis Delgado | CWS | DET | April 23, 2043 | 4-1 | 3 | 3 | 4 | 3 | 3 | 1 | 93 |
| 15 | Jorge Camacho | ARI | DET | May 10, 2043 | 9-8 | 5 | 5 | 4 | 1 | 2 | 1 | 92 |
| 16 | Juan Mariscal | SD | ARI | July 5, 2043 | 15-4 | 5 | 4 | 3 | 2 | 4 | 1 | 92 |
| 17 | Amari Rahmaan | NYM | ATL | April 2, 2043 | 11-3 | 4 | 3 | 4 | 2 | 4 | 1 | 91 |
| 18 | Chris Breene | CIN | DET | July 14, 2043 | 9-4 | 4 | 3 | 6 | 2 | 2 | 1 | 91 |
| 19 | Andy Frazee | COL | SF | April 22, 2043 | 18-6 | 4 | 3 | 4 | 2 | 3 | 2 | 89 |
| 20 | Adan Levandoski | TOR | NYY | July 15, 2043 | 15-4 | 5 | 3 | 7 | 2 | 2 | 0 | 89 |
| 21 | Bobby Tracey | LAD | CWS | June 5, 2043 | 14-2 | 5 | 3 | 6 | 2 | 3 | 0 | 89 |
| 22 | Luis Pimentel | SD | DET | May 30, 2043 | 8-7 | 5 | 3 | 7 | 2 | 2 | 0 | 89 |
| 23 | Juan Miramontes | OAK | CLE | April 13, 2043 | 10-8 | 3 | 2 | 5 | 2 | 3 | 2 | 88 |
| 24 | Juan Medina | MON | PHI | April 2, 2043 | 8-7 | 6 | 3 | 5 | 3 | 3 | 1 | 88 |
| 25 | Daizo Takaki | DET | BAL | May 19, 2043 | 9-10 | 6 | 4 | 4 | 3 | 3 | 0 | 88 |
| 26 | Juan Piriz | LAD | CWS | June 5, 2043 | 14-2 | 3 | 2 | 4 | 2 | 4 | 2 | 88 |
| 27 | Humberto Ramirez | SEA | CLE | April 26, 2043 | 10-11 | 5 | 4 | 4 | 2 | 3 | 0 | 87 |
| 28 | Dave Rucker | NYM | PHI | April 29, 2043 | 24-1 | 5 | 3 | 5 | 2 | 3 | 1 | 87 |
| 29 | Juan Arroyo | NYY | KC | April 17, 2043 | 10-4 | 4 | 3 | 5 | 1 | 3 | 1 | 86 |
| 30 | Luis Rosales | NYM | PIT | May 12, 2043 | 8-1 | 4 | 3 | 6 | 2 | 2 | 0 | 86 |