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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Brien, Andy | C | Baltimore Orioles | 32 | 08/06/2015 | Brooklyn | USA | Right | Right | 6' 2" | 205 lbs | $4,200,000 |
| O'Brien, Mike | SP | Oakland Athletics | 30 | 09/09/2017 | Newburgh Heights | USA | Right | Left | 6' 0" | 200 lbs | $535,000 |
| O'Brien, Sean | SP | Free Agent | 17 | 10/19/2029 | Springfield | USA | Right | Right | 5' 11" | 165 lbs | - |
| O'Mara, Joel | RP | Chicago Cubs | 31 | 12/29/2015 | Castroville | USA | Right | Left | 6' 6" | 200 lbs | $1,500,000 |
| O'Neil, Jonathan | SP | Free Agent | 17 | 03/10/2030 | Melville | USA | Right | Right | 6' 6" | 190 lbs | - |
| Oakes, R.J. | RF | Pittsburgh Pirates | 27 | 04/26/2020 | Wahiawa | USA | Left | Right | 6' 2" | 200 lbs | $1,378,000 |
| Oakley, Ryan | 3B | Free Agent | 16 | 03/24/2031 | Willard | USA | Left | Right | 5' 10" | 160 lbs | - |
| Oates, Jason | RP | Free Agent | 22 | 03/30/2025 | Tinicum Township | USA | Right | Right | 6' 0" | 180 lbs | - |
| Obermann, Nate | CF | Free Agent | 21 | 05/19/2026 | Marshfield | USA | Left | Left | 6' 1" | 165 lbs | - |
| Oca, AntoÕio | 3B | Cincinnati Reds | 23 | 12/19/2023 | Maracaibo | VEN | Left | Right | 6' 4" | 200 lbs | $535,000 |
| Ocasio, Vito | CF | Washington Nationals | 35 | 11/08/2011 | Cotuí | DOM | Right | Right | 6' 2" | 200 lbs | $18,300,000 |
| Ocejo, Victor | SP | Free Agent | 16 | 11/05/2030 | Hainesville | USA | Right | Right | 6' 1" | 170 lbs | - |
| Ochoa, Ernesto | LF | Texas Rangers | 29 | 01/16/2018 | Memphis | USA | Right | Right | 6' 2" | 200 lbs | $535,000 |
| Ochs, Kevin | SP | Free Agent | 21 | 09/01/2026 | Littleton | USA | Right | Right | 6' 5" | 190 lbs | - |
| Odems, Stephon | SP | Free Agent | 20 | 06/04/2027 | Severn | USA | Right | Right | 6' 6" | 190 lbs | - |
| Odom, Jarred | RP | Free Agent | 36 | 08/24/2011 | Novato | USA | Right | Right | 6' 0" | 200 lbs | - |
| Oelze, Jim | RF | Free Agent | 17 | 08/28/2030 | Houston | USA | Left | Left | 6' 2" | 180 lbs | - |
| Ohl, Eric | SP | San Francisco Giants | 29 | 12/28/2017 | St. Martin | USA | Right | Right | 6' 10" | 200 lbs | $13,800,000 |
| Okoh, Amari | CL | Texas Rangers | 32 | 06/30/2015 | East Hemet | USA | Right | Right | 6' 2" | 200 lbs | $14,000,000 |
| Okolo, Damani | SP | Free Agent | 20 | 12/30/2026 | Concord | USA | Right | Right | 6' 0" | 175 lbs | - |
| Olivas, Esteban | SS | San Diego Padres | 31 | 09/21/2015 | Candelaria | PUR | Right | Right | 6' 5" | 200 lbs | $4,000,000 |
| Olivia, Alex | SP | New York Mets | 18 | 01/04/2029 | Santo Domingo | DOM | Left | Right | 6' 2" | 185 lbs | - |
| Olsen, Mike | 3B | Los Angeles Dodgers | 36 | 09/05/2011 | Los Angeles | USA | Right | Right | 6' 2" | 205 lbs | $8,000,000 |
| Olson, Pat | CF | Free Agent | 20 | 01/24/2027 | Lander | USA | Right | Right | 6' 1" | 190 lbs | - |
| Onofre, Lupe | 2B | Florida Marlins | 30 | 02/22/2017 | San Juan de la Maguana | DOM | Right | Right | 6' 4" | 200 lbs | $900,000 |
| Ordaz, Bob | SP | Free Agent | 17 | 07/25/2030 | Emporium | USA | Switch | Right | 6' 2" | 180 lbs | - |
| Orona, Edward | SP | Chicago Cubs | 17 | 02/18/2030 | Baruta | VEN | Right | Right | 6' 4" | 190 lbs | - |
| Orozco, Jorge | RF | Detroit Tigers | 26 | 12/17/2020 | Charallave | VEN | Left | Left | 6' 2" | 200 lbs | $535,000 |
| Orozco, Juan | C | Colorado Rockies | 25 | 08/04/2022 | Kalamazoo | USA | Right | Right | 6' 6" | 210 lbs | $535,000 |
| Orozco, Juan | RP | Free Agent | 25 | 02/15/2022 | Clearwater | USA | Left | Left | 6' 2" | 190 lbs | - |
| Orozco, Luis | SP | Free Agent | 31 | 03/28/2016 | Washington | USA | Left | Right | 6' 7" | 205 lbs | - |
| Ortis, Alejandro | RP | Atlanta Braves | 17 | 08/06/2030 | Chinandega | NCA | Left | Right | 6' 4" | 185 lbs | - |
| Ortiz, Melvin | SP | Free Agent | 17 | 03/05/2030 | Canaan | USA | Right | Right | 6' 4" | 180 lbs | - |
| Ortiz, Ricky | C | San Diego Padres | 18 | 08/27/2029 | Santiago | DOM | Right | Right | 5' 10" | 165 lbs | - |
| Osborn, Zachary | C | Free Agent | 15 | 10/08/2031 | Brooklyn | USA | Switch | Right | 5' 11" | 170 lbs | - |
| Osborne, Andy | CF | San Diego Padres | 28 | 06/28/2019 | Corvallis | USA | Right | Right | 6' 2" | 200 lbs | $535,000 |
| Osorio, Ismael | SP | Free Agent | 21 | 07/29/2026 | Guaynabo | PUR | Right | Right | 5' 10" | 155 lbs | - |
| Osorio, Juan | SP | Boston Red Sox | 33 | 07/11/2014 | Santo Domingo | DOM | Left | Right | 6' 1" | 190 lbs | $23,200,000 |
| Ostapenko, Jared | LF | Houston Astros | 25 | 03/23/2022 | Palm Bay | USA | Left | Left | 6' 0" | 185 lbs | $535,000 |
| Ostendorf, Danny | CF | Free Agent | 21 | 06/07/2026 | East Stroudsburg | USA | Right | Right | 6' 3" | 185 lbs | - |
| Ostertag, Chris | RP | Washington Nationals | 36 | 07/15/2011 | Tucson | USA | Left | Left | 6' 4" | 200 lbs | $26,000,000 |
| Ostrander, Corey | 2B | Free Agent | 17 | 01/13/2030 | Hometown | USA | Right | Right | 6' 2" | 180 lbs | - |
| Osuna, Miguel | C | Free Agent | 16 | 05/14/2031 | Florence-Graham | USA | Right | Right | 6' 0" | 170 lbs | - |
| Othon, Juan | SS | Arizona Diamondbacks | 31 | 03/28/2016 | Santiago | DOM | Right | Right | 6' 3" | 200 lbs | $1,400,000 |
| Owens, Jay | SP | Free Agent | 15 | 10/31/2031 | Rhinelander | USA | Left | Left | 6' 5" | 180 lbs | - |
| Owens, Pat | RP | Free Agent | 28 | 01/29/2019 | Washington | USA | Right | Right | 6' 0" | 200 lbs | - |
| Owusu, Ajani | SS | Seattle Mariners | 30 | 01/31/2017 | North Vandergrift-Pleasant View | USA | Right | Right | 6' 4" | 195 lbs | $4,000,000 |
| Owusu, Nehemiah | SS | Free Agent | 19 | 10/23/2027 | Chicago | USA | Right | Right | 6' 2" | 170 lbs | - |
