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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Julio | SP | Tennessee Smokies | 22 | 06/20/2009 | La Romana | DOM | Switch | Right | 6' 1" | 185 lbs | - |
| Salazar, Joaquin | RP | Free Agent | 29 | 11/05/2001 | Menlo Park | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sale, Joe | SP | Chattanooga Lookouts | 25 | 09/18/2005 | Philadelphia | USA | Right | Right | 6' 6" | 210 lbs | - |
| Sampson, Chris | RP | Rocket City Trash Pandas | 23 | 12/04/2007 | Miami | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sanchez, Frank | RP | Biloxi Shuckers | 24 | 03/22/2007 | Stockton | USA | Right | Right | 6' 2" | 200 lbs | - |
| Santana, Angel | RP | Tennessee Smokies | 28 | 02/27/2003 | San Pedro de Macorís | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Santillan, Eli | SS | Biloxi Shuckers | 22 | 10/24/2008 | Araure | VEN | Right | Right | 6' 3" | 190 lbs | - |
| Sarabia, Cortez | RP | Mississippi Braves | 26 | 10/23/2004 | San Diego | USA | Right | Right | 5' 9" | 185 lbs | - |
| Savoy, Phil | 2B | Birmingham Barons | 25 | 10/29/2005 | Yonkers | USA | Right | Right | 6' 1" | 205 lbs | - |
| Scheerer, Dan | LF | Pensacola Blue Wahoos | 25 | 04/06/2006 | Salinas | USA | Right | Right | 5' 11" | 200 lbs | - |
| Schmitt, Jeff | 3B | Tennessee Smokies | 28 | 10/06/2002 | New York | USA | Right | Right | 6' 2" | 200 lbs | - |
| Schreiner, Mitch | SP | Free Agent | 26 | 08/02/2005 | Galesburg | USA | Left | Right | 6' 2" | 195 lbs | - |
| Schubert, Mike | C | Rocket City Trash Pandas | 25 | 02/06/2006 | Altamonte Springs | USA | Right | Right | 6' 4" | 205 lbs | - |
| Serrano, Jhoniel | RP | Free Agent | 27 | 10/17/2003 | Unknown | VEN | Right | Right | 6' 0" | 195 lbs | - |
| Serrano, Jose | SP | Tennessee Smokies | 24 | 06/30/2007 | Veragua | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Silva, Eddie | 2B | Mississippi Braves | 25 | 08/21/2006 | East Lansing | USA | Right | Right | 6' 3" | 200 lbs | - |
| Simms, Chris | LF | Birmingham Barons | 24 | 05/02/2007 | Norfolk | USA | Left | Left | 6' 4" | 210 lbs | - |
| Sirotka Jr., Mike | CF | Birmingham Barons | 29 | 07/10/2002 | Houston | USA | Left | Left | 6' 2" | 200 lbs | - |
| Slaney, Eli | SP | Free Agent | 26 | 06/10/2005 | Ormond Beach | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Omarion | RP | Pensacola Blue Wahoos | 27 | 09/12/2003 | Chicago | USA | Switch | Left | 5' 8" | 180 lbs | - |
| Solis, Jose | SP | Chattanooga Lookouts | 25 | 12/20/2005 | Santo Domingo | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Solis, Omar | SP | Birmingham Barons | 26 | 05/02/2005 | New York | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sotelo, Daniel | SP | Pensacola Blue Wahoos | 22 | 10/11/2008 | El Limón | VEN | Right | Right | 6' 7" | 200 lbs | - |
| Spencer, Joey | RP | Chattanooga Lookouts | 23 | 12/09/2007 | Gibbstown | USA | Left | Left | 6' 1" | 200 lbs | - |
| Spuhler, Sam | CL | Rocket City Trash Pandas | 22 | 12/09/2008 | Providence | USA | Right | Left | 6' 3" | 190 lbs | - |
| Stacey, Chris | RP | Free Agent | 32 | 05/19/1999 | Havelock | USA | Switch | Right | 5' 10" | 195 lbs | - |
| Steelman, Devon | SP | Rocket City Trash Pandas | 24 | 04/12/2007 | Baltimore | USA | Right | Left | 6' 1" | 200 lbs | - |
| Steiner, Bobby | RP | Pensacola Blue Wahoos | 24 | 12/22/2006 | Dover | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stevenson, Dusty | RP | Birmingham Barons | 24 | 10/16/2006 | Winston-Salem | USA | Right | Right | 6' 2" | 200 lbs | - |
| Stum, Kevin | 2B | Chattanooga Lookouts | 29 | 09/10/2001 | Highland Park | USA | Right | Right | 6' 0" | 205 lbs | - |
