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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saldivar, Jorge | SP | Pensacola Blue Wahoos | 25 | 11/05/2024 | Barcelona | VEN | Switch | Right | 6' 4" | 200 lbs | - |
| Salgado, Juan | 3B | Biloxi Shuckers | 24 | 05/18/2026 | Austin | USA | Left | Right | 6' 3" | 200 lbs | $545,000 |
| Santiage, Rogelio | RP | Mobile BayBears | 26 | 01/03/2024 | San Pedro de Macorís | DOM | Left | Left | 6' 2" | 200 lbs | - |
| Sato, Yasuji | SP | Chattanooga Lookouts | 26 | 08/07/2023 | Toyota | JPN | Right | Right | 6' 7" | 200 lbs | - |
| Saunders, Bobby | CF | Nashville Sounds | 25 | 09/14/2024 | Council Bluffs | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sausser, Josh | CF | Montgomery Biscuits | 26 | 05/11/2024 | Pine Bluff | USA | Right | Right | 6' 1" | 205 lbs | - |
| Savvides, Eric | CF | Jacksonville Jumbo Shrimp | 26 | 11/21/2023 | Tooele | USA | Right | Left | 6' 0" | 200 lbs | - |
| Schaf, Kevin | SP | Jacksonville Jumbo Shrimp | 26 | 05/15/2024 | Tamalpais-Homestead Valley | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schmider, Dave | RP | Montgomery Biscuits | 27 | 12/30/2022 | Dillsburg | USA | Left | Left | 6' 4" | 185 lbs | - |
| Sebion, Oscar | RP | Montgomery Biscuits | 25 | 08/21/2024 | Columbus | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sells, Steve | RP | Jacksonville Jumbo Shrimp | 22 | 10/17/2027 | New York | USA | Right | Right | 6' 1" | 195 lbs | - |
| Serratelli, Josh | LF | Chattanooga Lookouts | 26 | 08/27/2023 | Houston | USA | Left | Right | 6' 6" | 200 lbs | - |
| Sesay, Tyshawn | SP | Tennessee Smokies | 23 | 07/11/2027 | Pinecrest | USA | Right | Right | 6' 2" | 200 lbs | - |
| Shaeffer, Johnny | 2B | Pensacola Blue Wahoos | 27 | 09/13/2022 | Missoula | USA | Right | Right | 6' 2" | 205 lbs | $545,000 |
| Shortt, Andy | SP | Tennessee Smokies | 23 | 11/25/2026 | Ft. Worth | USA | Left | Right | 6' 1" | 185 lbs | - |
| Slone, Dan | C | Mississippi Braves | 25 | 03/21/2025 | New Haven | USA | Right | Right | 6' 0" | 200 lbs | - |
| Soto, Sergio | 3B | Biloxi Shuckers | 25 | 07/30/2025 | Gassville | USA | Right | Right | 6' 4" | 200 lbs | - |
| Spencer, Eric | RF | Chattanooga Lookouts | 22 | 10/30/2027 | Columbia | USA | Right | Right | 6' 0" | 195 lbs | - |
| Springer, Rob | RP | Free Agent | 28 | 02/05/2022 | Independence | USA | Left | Left | 6' 6" | 200 lbs | - |
| St. George, Harland | C | Birmingham Barons | 24 | 11/23/2025 | South Snyderville Basin | USA | Switch | Right | 6' 0" | 205 lbs | - |
| Steimle, Terrance | RP | Free Agent | 27 | 01/31/2023 | Carson | USA | Right | Right | 6' 2" | 205 lbs | - |
| Stevens, Eric | 2B | Chattanooga Lookouts | 26 | 06/04/2024 | Farmington | USA | Left | Right | 6' 2" | 200 lbs | - |
| Stimage, Omarion | CF | Jackson Generals | 27 | 11/17/2022 | Oxnard | USA | Right | Left | 6' 3" | 195 lbs | - |
| Strickland, Tim | SP | Biloxi Shuckers | 24 | 05/21/2026 | Clanton | USA | Left | Left | 5' 10" | 185 lbs | - |
| Sullivan, Chris | SP | Tennessee Smokies | 26 | 04/04/2024 | Chino | USA | Right | Right | 6' 9" | 200 lbs | - |
| Sweeney, Billy | SP | Mississippi Braves | 24 | 08/12/2025 | Green Bay | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sweeney, Kevin | RP | Tennessee Smokies | 26 | 05/31/2024 | Cleveland | USA | Right | Right | 5' 10" | 185 lbs | - |
| Swick, Whitney | SP | Chattanooga Lookouts | 24 | 04/26/2026 | Boston | USA | Switch | Right | 6' 2" | 195 lbs | - |
