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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | W | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Danny Hultzen# | 168 | 2012-2024 | |
| 2 | Clayton Kershaw# | 156 | 2012-2024 | |
| 3 | Nathan Eovaldi# | 153 | 2012-2024 | |
| 4 | Felix Hernandez | 141 | 2012-2022 | |
| 5 | Zack Greinke# | 139 | 2012-2024 | |
| 6 | Tim Lincecum# | 138 | 2012-2023 | |
| 7 | Stephen Strasburg# | 132 | 2012-2024 | |
| 8 | Jon Lester* | 131 | 2012-2021 | |
| 9 | Sean Gilmartin# | 129 | 2012-2024 | |
| 10 | Josh Johnson | 127 | 2012-2021 | |
| 10 | Jonathon Niese | 127 | 2012-2022 | |
| 12 | Jarred Cosart# | 122 | 2012-2024 | |
| 13 | Justin Verlander* | 119 | 2012-2020 | |
| 14 | Josh Collmenter | 117 | 2012-2022 | |
| 15 | Miguel Pineda# | 115 | 2016-2024 | |
| 16 | Jordan Zimmermann | 112 | 2012-2021 | |
| 17 | Trevor Bauer# | 108 | 2012-2024 | |
| 17 | Gerrit Cole# | 108 | 2012-2024 | |
| 17 | Ryan Copeland# | 108 | 2015-2024 | |
| 17 | Brad Peacock | 108 | 2012-2023 | |
| 21 | Brandon Morrow | 107 | 2012-2019 | |
| 21 | Keyvius Sampson# | 107 | 2014-2024 | |
| 23 | Yu Darvish | 106 | 2012-2021 | |
| 24 | Parker Markel# | 104 | 2014-2024 | |
| 24 | David Price | 104 | 2012-2019 | |
| 26 | Phil Hughes | 103 | 2012-2021 | |
| 26 | Casey Kelly# | 103 | 2013-2023 | |
| 28 | Lucas Giolito# | 102 | 2016-2024 | |
| 29 | Gio Gonzalez | 100 | 2012-2020 | |
| 30 | Brandon Beachy | 99 | 2012-2022 | |
| 30 | Tommy Hanson | 99 | 2012-2020 | |
| 32 | Mark Appel# | 97 | 2014-2024 | |
| 32 | Madison Bumgarner# | 97 | 2012-2024 | |
| 32 | Dylan Bundy# | 97 | 2012-2023 | |
| 32 | Alberto Vega# | 97 | 2016-2024 | |
| 36 | Matt Moore | 96 | 2012-2020 | |
| 37 | Neftali Feliz | 95 | 2012-2021 | |
| 37 | Mat Latos# | 95 | 2012-2022 | |
| 37 | Juan Nicasio | 95 | 2012-2021 | |
| 40 | Michael Pineda# | 94 | 2012-2022 | |
| 41 | Trevor Cahill | 92 | 2012-2022 | |
| 41 | Josh Tomlin# | 92 | 2012-2022 | |
| 43 | Lúcio Cruzado | 90 | 2014-2022 | |
| 44 | Steve White# | 89 | 2016-2024 | |
| 45 | Archie Bradley# | 88 | 2015-2024 | |
| 45 | Shelby Miller# | 88 | 2012-2022 | |
| 45 | Max Scherzer | 88 | 2012-2023 | |
| 48 | Jordan Lyles# | 87 | 2012-2023 | |
| 49 | Sonny Gray# | 85 | 2012-2022 | |
| 49 | C.J. Wilson | 85 | 2012-2018 | |
| 51 | Bill Black# | 84 | 2017-2024 | |
| 51 | Vance Worley | 84 | 2012-2020 | |
| 53 | Tadakuni Fujita | 83 | 2014-2019 | |
| 53 | Justin Hooper# | 83 | 2018-2024 | |
| 55 | Henderson Alvarez | 82 | 2012-2018 | |
| 55 | Tom Milone | 82 | 2012-2018 | |
| 57 | James Kaprielian# | 81 | 2016-2024 | |
| 58 | Craig Cooper# | 80 | 2016-2024 | |
| 58 | Broderick Wilson# | 80 | 2016-2024 | |
| 60 | Matt Cain | 79 | 2012-2020 | |
| 60 | Mike Minor | 79 | 2012-2018 | |
| 62 | Clay Buchholz | 78 | 2012-2018 | |
| 62 | Zach Lee# | 78 | 2013-2024 | |
| 62 | Manuel Reyes# | 78 | 2014-2024 | |
| 62 | Chris Sale# | 78 | 2012-2024 | |
| 62 | Michael Wacha# | 78 | 2016-2024 | |
| 67 | Brady Aiken# | 77 | 2017-2024 | |
| 68 | Wily Peralta# | 76 | 2012-2021 | |
| 69 | Albert Suarez# | 75 | 2014-2023 | |
| 70 | Manny Banuelos# | 74 | 2012-2019 | |
| 70 | Scott Clark# | 74 | 2015-2022 | |
| 70 | James Paxton# | 74 | 2012-2023 | |
| 73 | Andrew Morales# | 73 | 2018-2024 | |
| 73 | Tyler Pill# | 73 | 2014-2023 | |
| 73 | Edward Reith# | 73 | 2018-2024 | |
| 73 | Mark Sorensen | 73 | 2013-2022 | |
| 77 | Carlos Meza# | 72 | 2014-2024 | |
| 77 | Jered Weaver | 72 | 2012-2017 | |
| 79 | Paul Erickson# | 71 | 2016-2024 | |
| 79 | Daniel Hudson# | 71 | 2012-2022 | |
| 79 | Jarrod Parker# | 71 | 2012-2021 | |
| 82 | Jordan Cote# | 70 | 2015-2024 | |
| 82 | Steven Matz# | 70 | 2016-2023 | |
| 82 | Raynel Velette# | 70 | 2015-2024 | |
| 85 | Michael Matuella# | 69 | 2016-2024 | |
| 85 | James Shields | 69 | 2012-2017 | |
| 87 | Kevin Comer# | 68 | 2015-2024 | |
| 87 | Jeffery LeBlanc# | 68 | 2018-2024 | |
| 89 | Walker Buehler# | 67 | 2017-2024 | |
| 89 | Aroldis Chapman# | 67 | 2012-2024 | |
| 89 | Pedro Magana# | 67 | 2018-2024 | |
| 89 | Jamie Widner# | 67 | 2018-2024 | |
| 93 | Trevor Bell | 66 | 2012-2017 | |
| 93 | Cole Hamels | 66 | 2012-2020 | |
| 93 | Ian Kennedy | 66 | 2012-2019 | |
| 93 | Anthony Meo# | 66 | 2013-2022 | |
| 97 | Simon Castro# | 65 | 2012-2020 | |
| 97 | John Lamb# | 65 | 2014-2024 | |
| 99 | Kolby Allard# | 64 | 2018-2024 | |
| 99 | Chad Billingsley | 64 | 2012-2020 |
