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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Clayton Kershaw# | 2451.0 | 2012-2024 | |
| 2 | Zack Greinke# | 2423.0 | 2012-2024 | |
| 3 | Danny Hultzen# | 2417.0 | 2012-2024 | |
| 4 | Nathan Eovaldi# | 2280.0 | 2012-2024 | |
| 5 | Sean Gilmartin# | 2170.0 | 2012-2024 | |
| 6 | Stephen Strasburg# | 2164.0 | 2012-2024 | |
| 7 | Josh Collmenter | 2121.0 | 2012-2022 | |
| 8 | Brad Peacock | 2052.0 | 2012-2023 | |
| 9 | Tim Lincecum# | 2047.0 | 2012-2023 | |
| 10 | Felix Hernandez | 2036.0 | 2012-2022 | |
| 11 | Jarred Cosart# | 1966.0 | 2012-2024 | |
| 12 | Josh Johnson | 1965.0 | 2012-2021 | |
| 13 | Justin Verlander* | 1924.0 | 2012-2020 | |
| 14 | Trevor Bauer# | 1905.0 | 2012-2024 | |
| 15 | Gerrit Cole# | 1902.0 | 2012-2024 | |
| 16 | Jordan Zimmermann | 1876.0 | 2012-2021 | |
| 16 | Jonathon Niese | 1876.0 | 2012-2022 | |
| 18 | Jon Lester* | 1845.0 | 2012-2021 | |
| 19 | Parker Markel# | 1784.0 | 2014-2024 | |
| 20 | Michael Pineda# | 1783.0 | 2012-2022 | |
| 21 | Madison Bumgarner# | 1774.0 | 2012-2024 | |
| 22 | Phil Hughes | 1772.0 | 2012-2021 | |
| 23 | Keyvius Sampson# | 1771.0 | 2014-2024 | |
| 24 | Juan Nicasio | 1763.0 | 2012-2021 | |
| 25 | Jordan Lyles# | 1741.0 | 2012-2023 | |
| 26 | Josh Tomlin# | 1724.0 | 2012-2022 | |
| 27 | Yu Darvish | 1723.0 | 2012-2021 | |
| 28 | Shelby Miller# | 1721.0 | 2012-2022 | |
| 29 | Brandon Beachy | 1714.0 | 2012-2022 | |
| 30 | Mat Latos# | 1707.0 | 2012-2022 | |
| 31 | Casey Kelly# | 1693.0 | 2013-2023 | |
| 32 | Tommy Hanson | 1691.0 | 2012-2020 | |
| 33 | Trevor Cahill | 1662.0 | 2012-2022 | |
| 34 | Miguel Pineda# | 1628.0 | 2016-2024 | |
| 35 | Mark Appel# | 1601.0 | 2014-2024 | |
| 36 | David Price | 1597.0 | 2012-2019 | |
| 37 | Gio Gonzalez | 1580.0 | 2012-2020 | |
| 38 | Dylan Bundy# | 1560.0 | 2012-2023 | |
| 39 | Ryan Copeland# | 1558.0 | 2015-2024 | |
| 40 | Matt Moore | 1548.0 | 2012-2020 | |
| 41 | Max Scherzer | 1527.0 | 2012-2023 | |
| 42 | Daniel Hudson# | 1520.0 | 2012-2022 | |
| 43 | Lucas Giolito# | 1496.0 | 2016-2024 | |
| 44 | Mark Sorensen | 1476.0 | 2013-2022 | |
| 45 | Archie Bradley# | 1474.0 | 2015-2024 | |
| 45 | Matt Cain | 1474.0 | 2012-2020 | |
| 47 | James Paxton# | 1460.0 | 2012-2023 | |
| 48 | Vance Worley | 1454.0 | 2012-2020 | |
| 49 | Steve White# | 1445.0 | 2016-2024 | |
| 50 | Chris Sale# | 1429.0 | 2012-2024 | |
| 51 | Brandon Morrow | 1427.0 | 2012-2019 | |
| 52 | Neftali Feliz | 1426.0 | 2012-2021 | |
| 53 | Sonny Gray# | 1413.0 | 2012-2022 | |
| 54 | Manny Banuelos# | 1401.0 | 2012-2019 | |
| 55 | Manuel Reyes# | 1386.0 | 2014-2024 | |
| 56 | Carlos Meza# | 1378.0 | 2014-2024 | |
| 57 | Alberto Vega# | 1369.0 | 2016-2024 | |
| 58 | Albert Suarez# | 1358.0 | 2014-2023 | |
| 59 | Scott Clark# | 1357.0 | 2015-2022 | |
| 60 | Michael Wacha# | 1353.0 | 2016-2024 | |
| 61 | Zach Lee# | 1336.0 | 2013-2024 | |
| 62 | Broderick Wilson# | 1330.0 | 2016-2024 | |
| 63 | Edwin Jackson | 1329.0 | 2012-2018 | |
| 64 | James Kaprielian# | 1316.0 | 2016-2024 | |
| 65 | Wily Peralta# | 1312.0 | 2012-2021 | |
| 66 | Tyler Pill# | 1302.0 | 2014-2023 | |
| 67 | Lúcio Cruzado | 1297.0 | 2014-2022 | |
| 68 | Justin Masterson | 1295.0 | 2012-2018 | |
| 69 | Jarrod Parker# | 1290.0 | 2012-2021 | |
| 70 | Jordan Cote# | 1288.0 | 2015-2024 | |
| 71 | Bill Black# | 1276.0 | 2017-2024 | |
| 72 | Michael Matuella# | 1259.0 | 2016-2024 | |
| 73 | Mike Minor | 1256.0 | 2012-2018 | |
| 74 | Brady Aiken# | 1247.0 | 2017-2024 | |
| 74 | Raynel Velette# | 1247.0 | 2015-2024 | |
| 76 | C.J. Wilson | 1237.0 | 2012-2018 | |
| 77 | Anthony Meo# | 1232.0 | 2013-2022 | |
| 78 | Henderson Alvarez | 1228.0 | 2012-2018 | |
| 79 | Tom Milone | 1224.0 | 2012-2018 | |
| 80 | Pat Swain# | 1220.0 | 2013-2021 | |
| 81 | Simon Castro# | 1211.0 | 2012-2020 | |
| 82 | Tyler Skaggs# | 1209.0 | 2013-2022 | |
| 83 | Wilmer Font | 1207.0 | 2012-2021 | |
| 84 | Richard White# | 1203.0 | 2017-2024 | |
| 85 | Chris Scalise# | 1200.0 | 2017-2024 | |
| 86 | Chad Billingsley | 1199.0 | 2012-2020 | |
| 87 | John Lamb# | 1193.0 | 2014-2024 | |
| 88 | Craig Cooper# | 1187.0 | 2016-2024 | |
| 89 | Tadakuni Fujita | 1185.0 | 2014-2019 | |
| 90 | Jered Weaver | 1183.0 | 2012-2017 | |
| 91 | Johnny Cueto | 1154.0 | 2012-2020 | |
| 92 | Steven Matz# | 1150.0 | 2016-2023 | |
| 93 | Kolby Allard# | 1148.0 | 2018-2024 | |
| 94 | Chris Volstad | 1147.0 | 2012-2019 | |
| 95 | Clay Buchholz | 1141.0 | 2012-2018 | |
| 96 | Ian Kennedy | 1131.0 | 2012-2019 | |
| 97 | Aroldis Chapman# | 1118.0 | 2012-2024 | |
| 98 | Kyle Cody# | 1114.0 | 2017-2024 | |
| 99 | Walker Buehler# | 1102.0 | 2017-2024 | |
| 100 | Andrew Morales# | 1098.0 | 2018-2024 |
