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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Evan Longoria# | 281 | 2012-2024 | |
| 2 | Nolan Arenado# | 243 | 2012-2024 | |
| 3 | Miguel Sano# | 217 | 2015-2024 | |
| 4 | Juan Francisco | 213 | 2012-2021 | |
| 5 | Mike Moustakas | 201 | 2012-2021 | |
| 6 | Pablo Sandoval | 174 | 2012-2022 | |
| 7 | Alonso Martínez# | 164 | 2017-2024 | |
| 8 | Kaleb Cowart# | 150 | 2015-2024 | |
| 9 | Rob Segedin# | 140 | 2015-2021 | |
| 10 | Maikel Franco# | 136 | 2015-2024 | |
| 11 | Javier García# | 127 | 2017-2024 | |
| 12 | Brett Lawrie# | 123 | 2012-2022 | |
| 12 | Santiago Mateo | 123 | 2012-2021 | |
| 14 | Will Middlebrooks | 110 | 2012-2021 | |
| 15 | Lonnie Chisenhall | 109 | 2012-2019 | |
| 15 | Chad Lewis# | 109 | 2015-2024 | |
| 17 | Anthony Rendon# | 105 | 2012-2024 | |
| 18 | David Wright | 103 | 2012-2018 | |
| 19 | Zack Cox | 90 | 2012-2020 | |
| 20 | Juan Espinoza# | 87 | 2017-2024 | |
| 20 | Cameron Gundy# | 87 | 2021-2024 | |
| 22 | Vladimir Guerrero Jr.# | 84 | 2020-2024 | |
| 23 | Corey Seager# | 83 | 2016-2024 | |
| 24 | Taylor Green | 82 | 2012-2017 | |
| 25 | Josh Vitters | 78 | 2012-2020 | |
| 26 | Brandon Hicks | 69 | 2012-2020 | |
| 27 | Alex Bregman# | 68 | 2018-2024 | |
| 27 | Hiroshi Nakamura# | 68 | 2018-2023 | |
| 29 | Ryan Zimmerman | 67 | 2012-2019 | |
| 30 | Taylor Sparks# | 63 | 2017-2024 | |
| 31 | Miguel Andujar# | 62 | 2017-2023 | |
| 31 | Tyler Townsend | 62 | 2014-2021 | |
| 33 | Mike Solaz# | 60 | 2017-2023 | |
| 34 | Kevin Youkilis | 59 | 2012-2015 | |
| 35 | Joey Moran# | 56 | 2020-2023 | |
| 35 | Ryan Wheeler | 56 | 2012-2022 | |
| 37 | Alfredo Morales# | 55 | 2018-2024 | |
| 38 | Daniel Fleming | 54 | 2017-2019 | |
| 38 | David Freese | 54 | 2012-2015 | |
| 40 | Garin Cecchini | 53 | 2015-2020 | |
| 40 | Oneil Cruz# | 53 | 2021-2024 | |
| 40 | António Morales# | 53 | 2020-2023 | |
| 43 | Andrew Hardy | 52 | 2017-2023 | |
| 44 | Alec Bohm# | 50 | 2020-2024 | |
| 44 | Rosell Herrera# | 50 | 2016-2020 | |
| 46 | Hanley Ramirez | 46 | 2012-2016 | |
| 47 | Mark Reynolds | 45 | 2012-2018 | |
| 48 | Marvin Grun# | 44 | 2019-2023 | |
| 48 | Brent Morel | 44 | 2012-2018 | |
| 50 | Jose Bautista | 43 | 2012-2018 | |
| 50 | Xavier Noonan# | 43 | 2019-2024 | |
| 52 | Jake Burger# | 41 | 2021-2024 | |
| 53 | Esteban Ortíz# | 40 | 2012-2020 | |
| 54 | Jared Goedert | 39 | 2013-2016 | |
| 55 | Mat Gamel | 38 | 2012-2018 | |
| 56 | Fernando Leguizamo# | 37 | 2021-2024 | |
| 56 | Alex Rodriguez | 37 | 2012-2015 | |
| 58 | Alex Castellanos | 36 | 2013-2018 | |
| 58 | Ryan Kerr# | 36 | 2022-2024 | |
| 60 | Yoan Moncada# | 35 | 2021-2023 | |
| 61 | Trey Ford# | 34 | 2017-2019 | |
| 61 | Joey Gallo# | 34 | 2018-2024 | |
| 61 | Matthew Kirkland | 34 | 2017-2021 | |
| 64 | Yugoro Kouki | 33 | 2017-2018 | |
| 64 | Kwan-yew Yeh# | 33 | 2020-2023 | |
| 66 | Brandon Inge | 31 | 2012-2014 | |
| 66 | Kyle Seager | 31 | 2012-2017 | |
| 68 | Kody Clemens# | 30 | 2020-2024 | |
| 68 | Bill La# | 30 | 2016-2024 | |
| 68 | Addison Maruszak | 30 | 2012-2020 | |
| 68 | Chris Owings# | 30 | 2014-2022 | |
| 68 | Travis Shaw# | 30 | 2016-2023 | |
| 73 | Luis D. Jimenez | 27 | 2012-2016 | |
| 73 | Manny Machado# | 27 | 2012-2024 | |
| 75 | Javier Baez# | 26 | 2015-2022 | |
| 75 | Nolan Jones# | 26 | 2022-2024 | |
| 75 | Jhonny Peralta | 26 | 2012-2018 | |
| 78 | Miguel Cabrera | 25 | 2012-2022 | |
| 78 | Blake DeWitt | 25 | 2012-2016 | |
| 80 | Conor Gillaspie | 23 | 2012-2018 | |
| 81 | Bobby Borchering | 22 | 2014-2017 | |
| 81 | James Darnell | 22 | 2012-2020 | |
| 81 | Nander De Sedas# | 22 | 2021-2024 | |
| 81 | Jordan Pacheco | 22 | 2012-2017 | |
| 81 | Tony Thompson | 22 | 2015-2019 | |
| 86 | Kolbrin Vitek | 21 | 2015-2020 | |
| 87 | Ricardo Pérez# | 20 | 2020-2024 | |
| 87 | Mathew Ryan# | 20 | 2019-2024 | |
| 89 | Matt Carpenter | 19 | 2012-2020 | |
| 89 | Nathan DeRemer# | 19 | 2022-2023 | |
| 89 | Ryan Vilade# | 19 | 2022-2024 | |
| 92 | Darin Holcomb | 18 | 2013-2016 | |
| 92 | Luis Pérez | 18 | 2015-2018 | |
| 92 | Richie Shaffer | 18 | 2016-2019 | |
| 95 | Enrico DeLeón# | 17 | 2014-2022 | |
| 95 | Marwin Gonzalez | 17 | 2012-2020 | |
| 95 | Matt Jenkins# | 17 | 2019-2024 | |
| 95 | Anthony Kerr# | 17 | 2018-2024 | |
| 95 | Aramis Ramirez | 17 | 2012-2013 | |
| 95 | Mickey Wiswall | 17 | 2014-2020 |
