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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Danny Hultzen# | .1895 | 2019 | |
| 2 | Lucas Giolito# | .1954 | 2022 | |
| 3 | Paul Erickson# | .1962 | 2023 | |
| 4 | Lucas Giolito# | .1970 | 2019 | |
| 5 | Clayton Kershaw# | .1975 | 2015 | |
| 6 | Shohei Ohtani# | .2000 | 2021 | |
| 7 | Stephen Strasburg# | .2003 | 2013 | |
| 8 | Colby Lewis | .2017 | 2012 | |
| 9 | Nathan Eovaldi# | .2021 | 2022 | |
| 9 | Stephen Strasburg# | .2021 | 2016 | |
| 11 | Matthew Liberatore# | .2024 | 2021 | |
| 12 | Scott Clark# | .2026 | 2018 | |
| 13 | Tommy Hanson | .2034 | 2012 | |
| 14 | Cody McCutc# | .2035 | 2021 | |
| 15 | Walker Buehler# | .2044 | 2022 | |
| 16 | Brady Aiken# | .2045 | 2022 | |
| 17 | Gio Gonzalez | .2047 | 2019 | |
| 18 | Nathan Eovaldi# | .2049 | 2017 | |
| 19 | Raynel Velette# | .2050 | 2016 | |
| 19 | Brandon Morrow | .2050 | 2015 | |
| 21 | Jon Lester* | .2052 | 2020 | |
| 21 | Bill Black# | .2052 | 2023 | |
| 23 | Paul Erickson# | .2064 | 2022 | |
| 24 | Jordan Lyles# | .2077 | 2019 | |
| 25 | Clayton Kershaw# | .2081 | 2013 | |
| 26 | Brandon Beachy | .2086 | 2012 | |
| 27 | Michael Pineda# | .2087 | 2015 | |
| 28 | Michael Matuella# | .2089 | 2020 | |
| 29 | Brandon Beachy | .2091 | 2014 | |
| 30 | Lucas Giolito# | .2093 | 2021 | |
| 31 | Jordan Lyles# | .2094 | 2022 | |
| 32 | Kolby Allard# | .2096 | 2019 | |
| 33 | Danny Hultzen# | .2101 | 2023 | |
| 33 | Justin Hooper# | .2101 | 2021 | |
| 35 | Clay Buchholz | .2102 | 2014 | |
| 36 | Danny Hultzen# | .2105 | 2021 | |
| 37 | Sean Gilmartin# | .2107 | 2016 | |
| 38 | Neil Ramirez | .2111 | 2013 | |
| 39 | Matthew Thompson# | .2112 | 2023 | |
| 40 | Duncan Duimelaar# | .2114 | 2021 | |
| 41 | Gary Griffith# | .2118 | 2022 | |
| 42 | Juan Dávila# | .2119 | 2023 | |
| 43 | Juan Trujillo# | .2121 | 2020 | |
| 44 | Alberto Vega# | .2125 | 2016 | |
| 45 | Zack Greinke# | .2131 | 2012 | |
| 46 | Albert Suarez# | .2132 | 2016 | |
| 46 | Mat Latos# | .2132 | 2013 | |
| 48 | Brandon Beachy | .2133 | 2013 | |
| 49 | Tadakuni Fujita | .2135 | 2015 | |
| 50 | Brad Peacock | .2137 | 2013 | |
| 51 | Lucas Giolito# | .2138 | 2018 | |
| 52 | Lucas Giolito# | .2139 | 2017 | |
| 53 | Edward Reith# | .2142 | 2020 | |
| 54 | Justin Hooper# | .2144 | 2020 | |
| 55 | Casey Kelly# | .2148 | 2020 | |
| 56 | Shao-qi Fung# | .2153 | 2019 | |
| 57 | Jonathon Niese | .2159 | 2015 | |
| 58 | David Price | .2162 | 2015 | |
| 59 | David Price | .2165 | 2014 | |
| 60 | Zack Greinke# | .2166 | 2016 | |
| 60 | Zack Wheeler | .2166 | 2013 | |
| 62 | Nathan Eovaldi# | .2167 | 2016 | |
| 62 | Dave Smith# | .2167 | 2021 | |
| 64 | Tommy Hanson | .2168 | 2017 | |
| 65 | Jon Lester* | .2170 | 2012 | |
| 66 | Stephen Strasburg# | .2172 | 2015 | |
| 67 | Tim Lincecum# | .2173 | 2019 | |
| 68 | Zack Greinke# | .2174 | 2013 | |
| 68 | Jordan Zimmermann | .2174 | 2017 | |
| 70 | Tim Lincecum# | .2178 | 2022 | |
| 71 | Matt Moore | .2179 | 2014 | |
| 72 | Ryan Copeland# | .2180 | 2018 | |
| 72 | Justin Hooper# | .2180 | 2019 | |
| 74 | Jesús Torres# | .2181 | 2022 | |
| 75 | Broderick Wilson# | .2184 | 2017 | |
| 76 | Rod Swift# | .2189 | 2019 | |
| 77 | Tim Lincecum# | .2190 | 2020 | |
| 77 | David Price | .2190 | 2012 | |
| 79 | Brandon Morrow | .2191 | 2014 | |
| 80 | Clayton Kershaw# | .2196 | 2020 | |
| 81 | Brandon Morrow | .2197 | 2013 | |
| 82 | Melvin Garner# | .2198 | 2019 | |
| 82 | Brandon Beachy | .2198 | 2016 | |
| 82 | Justin Hooper# | .2198 | 2022 | |
| 85 | Stephen Strasburg# | .2199 | 2014 | |
| 86 | Pedro Magana# | .2204 | 2020 | |
| 87 | Ryan Weathers# | .2206 | 2023 | |
| 87 | Archie Bradley# | .2206 | 2022 | |
| 89 | Justin Hooper# | .2208 | 2023 | |
| 90 | Ryan Copeland# | .2210 | 2017 | |
| 91 | Tim Lincecum# | .2211 | 2013 | |
| 92 | Martires Cadet# | .2212 | 2018 | |
| 93 | Stephen Strasburg# | .2215 | 2019 | |
| 93 | Rod Swift# | .2215 | 2023 | |
| 95 | Scott Clark# | .2216 | 2020 | |
| 96 | Taylor Guerrieri# | .2217 | 2014 | |
| 97 | David Price | .2218 | 2013 | |
| 98 | Clayton Kershaw# | .2221 | 2017 | |
| 99 | Josh Beckett | .2223 | 2012 | |
| 100 | Jeffery LeBlanc# | .2226 | 2023 |
