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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Christian Friedrich# | 144 | 2012-2022 | |
| 2 | Michael Fiers | 111 | 2012-2018 | |
| 3 | Charlie Furbush | 109 | 2012-2017 | |
| 4 | Jesse Darrah | 97 | 2015-2021 | |
| 5 | James Russell | 96 | 2012-2016 | |
| 6 | Jose Cisnero | 95 | 2013-2020 | |
| 7 | John Stilson | 90 | 2015-2021 | |
| 8 | Sean O'Sullivan | 83 | 2012-2018 | |
| 9 | Clayton Blackburn | 81 | 2016-2020 | |
| 9 | Brandon Martinez# | 81 | 2014-2022 | |
| 11 | Taylor Jungmann | 79 | 2014-2020 | |
| 12 | Matt Purke | 78 | 2014-2019 | |
| 13 | Chase Anderson | 76 | 2013-2014 | |
| 13 | Tyler Anderson# | 76 | 2013-2020 | |
| 13 | Edwar Cabrera | 76 | 2012-2018 | |
| 13 | Jeriome Hill# | 76 | 2019-2023 | |
| 13 | Joshua Hodges# | 76 | 2014-2018 | |
| 13 | David Phelps | 76 | 2013-2017 | |
| 13 | Blake Wood | 76 | 2012-2020 | |
| 20 | Erasmo Ramirez | 74 | 2013-2015 | |
| 20 | Victor Sanchez# | 74 | 2016-2024 | |
| 22 | Chad Jenkins | 72 | 2012-2022 | |
| 23 | Drew Taylor | 71 | 2012-2020 | |
| 23 | Daniel Winkler# | 71 | 2014-2024 | |
| 25 | Chad James# | 69 | 2012-2022 | |
| 25 | Cody Scarpetta | 69 | 2012-2019 | |
| 27 | Chad Bettis | 68 | 2015-2022 | |
| 27 | Randall Peña# | 68 | 2018-2022 | |
| 29 | Bryce Bandilla | 67 | 2013-2022 | |
| 29 | António Cruz# | 67 | 2015-2023 | |
| 31 | Miguel Gonzalez | 66 | 2013-2018 | |
| 31 | Nathan Karns | 66 | 2014-2019 | |
| 33 | Dae-Eun Rhee | 65 | 2012-2018 | |
| 34 | Neil Ramirez | 64 | 2012-2017 | |
| 34 | Andrew Walter | 64 | 2014-2019 | |
| 36 | Raul Alcantara | 63 | 2014-2021 | |
| 36 | Craig Missigman# | 63 | 2018-2021 | |
| 38 | John Hellweg | 62 | 2013-2022 | |
| 38 | José Ramos# | 62 | 2018-2023 | |
| 38 | Alex White | 62 | 2012-2017 | |
| 41 | Robbie Erlin | 61 | 2012-2017 | |
| 41 | Gustavo Gomez | 61 | 2015-2021 | |
| 41 | Junichi Tazawa | 61 | 2013-2017 | |
| 44 | Miguel De Los Santos | 59 | 2014-2022 | |
| 44 | Corey Kluber | 59 | 2012-2018 | |
| 46 | Kevin Gausman# | 58 | 2015-2022 | |
| 46 | Trevor Rosenthal# | 58 | 2013-2022 | |
| 48 | Duane Below | 57 | 2014-2018 | |
| 48 | José Castro# | 57 | 2013-2024 | |
| 48 | Pedro Figueroa | 57 | 2012-2016 | |
| 48 | Hayden Pierce# | 57 | 2019-2023 | |
| 48 | Zach Rivera# | 57 | 2017-2022 | |
| 48 | Fred Watts# | 57 | 2019-2022 | |
| 54 | Henry Sosa | 56 | 2012-2017 | |
| 55 | Joel Carreno | 55 | 2012-2017 | |
| 55 | Tyrell Jenkins# | 55 | 2015-2023 | |
| 55 | Bud Norris | 55 | 2012-2019 | |
| 55 | Enny Romero | 55 | 2013-2018 | |
| 55 | Will Smith | 55 | 2012-2023 | |
| 60 | Adrián Castillo# | 54 | 2018-2023 | |
| 60 | Brandon Erbe | 54 | 2012-2015 | |
| 62 | Taylore Cherry# | 53 | 2016-2021 | |
| 63 | Neftali Feliz | 52 | 2015-2023 | |
| 63 | Arturo Maltos-Garcia# | 52 | 2017-2022 | |
| 63 | Ethan Martin | 52 | 2013-2016 | |
| 63 | Garrett Richards | 52 | 2012-2020 | |
| 67 | Eduardo Rodriguez# | 51 | 2017-2023 | |
| 68 | David Cortéz# | 50 | 2019-2022 | |
| 68 | Scott Diamond | 50 | 2012-2015 | |
| 68 | Daniel Meadows | 50 | 2012-2017 | |
| 68 | Julio Teheran# | 50 | 2014-2024 | |
| 72 | Eduardo Fernández# | 49 | 2019-2024 | |
| 72 | Jeffrey MacIntosh# | 49 | 2017-2024 | |
| 72 | Bartolo Rivera# | 49 | 2019-2022 | |
| 72 | Ryan Verdugo | 49 | 2012-2016 | |
| 72 | Michael Ynoa# | 49 | 2018-2022 | |
| 77 | Paolo Espino | 48 | 2015-2017 | |
| 77 | Joe Kelly# | 48 | 2012-2014 | |
| 77 | Justin Marks | 48 | 2012-2018 | |
| 77 | Kurt Wunderlich | 48 | 2014-2018 | |
| 81 | Leonel Bastidas | 47 | 2015-2021 | |
| 81 | Zach McAllister | 47 | 2017-2020 | |
| 81 | Kyle McPherson | 47 | 2013-2021 | |
| 81 | Stolmy Pimentel | 47 | 2014-2015 | |
| 85 | Alexander Carreras | 46 | 2015-2018 | |
| 85 | J.A. Happ | 46 | 2012-2014 | |
| 85 | William Maddox# | 46 | 2017-2020 | |
| 85 | Clint Rosado# | 46 | 2019-2022 | |
| 85 | Matthew Summers# | 46 | 2014-2023 | |
| 90 | Trey Dillard# | 45 | 2022-2023 | |
| 90 | Javier García# | 45 | 2018-2024 | |
| 90 | Dillon Howard | 45 | 2016-2020 | |
| 90 | Ed Petty# | 45 | 2020-2023 | |
| 90 | Juan Sánchez# | 45 | 2021-2024 | |
| 95 | Michael Dubee | 44 | 2013-2018 | |
| 95 | Blake Hassebrock | 44 | 2014-2021 | |
| 95 | Carlos Pimentel | 44 | 2014-2017 | |
| 95 | Evan Rutckyj# | 44 | 2015-2020 | |
| 99 | Elvis Araujo | 43 | 2017-2021 | |
| 99 | Michael Broadway# | 43 | 2012-2022 |
