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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Tony | RP | Free Agent | 23 | 11/08/2000 | Santo Domingo | DOM | Switch | Right | 6' 2" | 200 lbs | - |
| Salazar, Luis Manuel | CF | Kannapolis Cannon Ballers | 21 | 04/07/2003 | La Cueva | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Salgado, Bryant | RP | Asheville Tourists | 24 | 03/02/2000 | Houston | USA | Right | Right | 6' 1" | 195 lbs | - |
| Sanburn, Nolan | SP | Free Agent | 32 | 07/21/1991 | Kokomo | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sapia, Luis | RP | Columbia Fireflies | 23 | 07/27/2000 | Maracaibo | VEN | Right | Right | 5' 10" | 170 lbs | - |
| Sasse, Michael | SP | Hickory Crawdads | 24 | 02/11/2000 | Omaha | USA | Right | Right | 6' 2" | 210 lbs | - |
| Saucke II, Casey | 3B | Delmarva Shorebirds | 20 | 07/24/2003 | Rochester | USA | Right | Right | 6' 3" | 200 lbs | - |
| Schaller, Benjamin | RP | West Virginia Power | 25 | 01/18/1999 | Longboat Key | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schoenwetter, Cole | SP | Charleston RiverDogs | 19 | 10/01/2004 | Santa Barbara | USA | Right | Right | 6' 3" | 195 lbs | - |
| Schroeder, Kyle | SP | Columbia Fireflies | 22 | 03/15/2002 | Redwood City | USA | Switch | Left | 6' 3" | 200 lbs | - |
| Scott, Drew | SP | Delmarva Shorebirds | 22 | 08/20/2001 | Clarksville | USA | Left | Left | 6' 3" | 200 lbs | - |
| Scott, John | RP | Free Agent | 24 | 09/02/1999 | New York | USA | Right | Right | 6' 2" | 195 lbs | - |
| Segura, Carlos | C | Augusta GreenJackets | 25 | 10/03/1998 | Santo Domingo | DOM | Right | Right | 6' 4" | 215 lbs | - |
| Sepúlveda, Alfredo | RP | West Virginia Power | 21 | 03/15/2003 | El Seibo | DOM | Right | Right | 6' 4" | 190 lbs | - |
| Shaw, Matt | SS | Delmarva Shorebirds | 22 | 11/06/2001 | Brimfield | USA | Right | Right | 5' 11" | 185 lbs | - |
| Shedler-McAvoy, Tyler | CF | Asheville Tourists | 25 | 06/21/1998 | Allendale | USA | Right | Right | 5' 10" | 205 lbs | - |
| Shelton, Mike | RP | Hickory Crawdads | 25 | 11/24/1998 | Simi Valley | USA | Right | Right | 6' 4" | 190 lbs | - |
| Short, Donnie | C | Augusta GreenJackets | 22 | 08/06/2001 | Lindenhurst | USA | Left | Right | 6' 1" | 195 lbs | - |
| Short, Mike | SP | Greensboro Grasshoppers | 25 | 04/06/1999 | Chandler | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shtolzberg, Ben | RF | Asheville Tourists | 20 | 10/26/2003 | Calabasas | USA | Right | Right | 6' 5" | 195 lbs | - |
| Silva, Eric | SP | Lakewood BlueClaws | 21 | 10/03/2002 | Laguna Beach | USA | Right | Right | 6' 0" | 175 lbs | - |
| Silva, Manuel | 1B | Hickory Crawdads | 27 | 02/11/1997 | Houston | USA | Right | Right | 6' 1" | 210 lbs | - |
| Silveira, Tristan | C | Free Agent | 25 | 08/20/1998 | Mérida | VEN | Right | Right | 5' 10" | 190 lbs | - |
| Simpson, Mark | 3B | West Virginia Power | 21 | 05/17/2002 | Grand Rapids | USA | Right | Right | 6' 3" | 190 lbs | - |
| Smith, D'Andre | SS | Greenville Drive | 22 | 05/10/2001 | Diamond Bar | USA | Right | Right | 5' 9" | 185 lbs | - |
| Smith, Gunnar | RP | Rome Braves | 24 | 01/04/2000 | Carteret | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, Noah | SS | Hickory Crawdads | 21 | 11/07/2002 | Chicago Heights | USA | Right | Right | 6' 1" | 190 lbs | - |
| Smith, Peyton | RP | Rome Braves | 22 | 09/26/2001 | Traverse City | USA | Right | Right | 6' 3" | 195 lbs | - |
| Smolinski, Carter | RP | Lexington Legends | 22 | 09/27/2001 | Boscobel | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smothers, Logan | RP | Greensboro Grasshoppers | 21 | 12/04/2002 | Athens | USA | Right | Right | 6' 3" | 200 lbs | - |
| Solís, Fernando | 3B | Kannapolis Cannon Ballers | 22 | 10/29/2001 | Guacara | VEN | Right | Right | 5' 11" | 185 lbs | - |
| Soto, Wilson | RF | Greensboro Grasshoppers | 20 | 09/18/2003 | La Vega | DOM | Left | Left | 6' 3" | 200 lbs | - |
| Southard, Jared | RP | Charleston RiverDogs | 23 | 10/04/2000 | Leander | USA | Right | Right | 6' 2" | 215 lbs | - |
| Stallings, Kyle | SP | Charleston RiverDogs | 19 | 10/10/2004 | Pittsburgh | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stephenson, Robert | SP | Free Agent | 31 | 02/24/1993 | Martinez | USA | Right | Right | 6' 2" | 200 lbs | - |
| Summers, Caden | SP | Lexington Legends | 21 | 08/16/2002 | Houston | USA | Left | Left | 6' 5" | 195 lbs | - |
| Sutcliffe, Andrew | RF | Rome Braves | 21 | 09/07/2002 | Chicago | USA | Left | Right | 6' 3" | 195 lbs | - |
| Swofford, Easton | 2B | Kannapolis Cannon Ballers | 20 | 11/11/2003 | Fayetteville | USA | Left | Right | 5' 11" | 175 lbs | - |
| Sykora, Travis | SP | Charleston RiverDogs | 19 | 04/28/2004 | Round Rock | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sánchez, Roberto | C | Free Agent | 22 | 03/18/2002 | Santo Domingo | DOM | Right | Right | 6' 4" | 205 lbs | - |
