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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Jaime | RP | Puget Sound Northmen | 24 | 02/09/2021 | Boise | USA | Switch | Right | 6' 2" | 185 lbs | - |
| Salinas, Juan | SP | Cleveland Spiders | 32 | 04/07/2013 | Larreynaga | NCA | Left | Right | 6' 2" | 195 lbs | - |
| Samurakami, Matabei | SP | Free Agent | 30 | 01/20/2015 | Tokyo | JPN | Left | Right | 6' 1" | 200 lbs | - |
| Sanders, Brian | CF | Mexico City Diablos Rojos | 25 | 05/09/2020 | Troy | USA | Right | Right | 6' 0" | 165 lbs | - |
| Sanders, Daron | 1B | San Antonio Blizzard | 31 | 04/13/2014 | Marble Falls | USA | Right | Right | 6' 1" | 190 lbs | - |
| Santos, Lorenzo | SS | Free Agent | 27 | 10/31/2017 | El Centro | USA | Right | Right | 6' 3" | 200 lbs | - |
| Santos, Michael | 3B | Pukalani Paniolos | 27 | 01/23/2018 | Glendale | USA | Right | Right | 6' 1" | 205 lbs | $300,000 |
| Sasaki, Hisayuki | 3B | Puget Sound Northmen | 24 | 06/24/2021 | Tomisato | JPN | Right | Right | 6' 5" | 200 lbs | $300,000 |
| Schaefer, Cliff | 3B | Charleston Frasers | 28 | 03/24/2017 | Denison | USA | Right | Right | 6' 2" | 195 lbs | $300,000 |
| Schaeffer, Josh | RF | Kensington Wolfpack | 24 | 09/23/2020 | Saint Charles | USA | Left | Left | 6' 1" | 200 lbs | - |
| Schmitt, Kyle | 3B | Free Agent | 27 | 06/22/2018 | Canyon Lake | USA | Right | Right | 6' 0" | 200 lbs | - |
| Scott, Chuck | RP | Asheville Spitfires | 26 | 07/02/2019 | Dyersburg | USA | Switch | Right | 6' 2" | 200 lbs | $300,000 |
| Scott, Jacob | SP | Arizona Bay Lizards | 24 | 11/24/2020 | River Forest | USA | Right | Right | 6' 6" | 200 lbs | - |
| Scott, John | 1B | Free Agent | 26 | 05/16/2019 | Mechanicsville | USA | Right | Right | 6' 3" | 200 lbs | - |
| Scott, Tom | C | Las Vegas Lightning | 27 | 02/17/2018 | Sparta | USA | Right | Right | 6' 1" | 200 lbs | - |
| Segura, Juan | C | Asheville Spitfires | 24 | 06/02/2021 | Panthersville | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sepúlveda, Gabriel | CF | Asheville Spitfires | 22 | 11/21/2022 | Flower Mound | USA | Right | Right | 6' 3" | 185 lbs | - |
| Serna, Eugene | SP | Las Vegas Lightning | 23 | 01/10/2022 | Weslaco | USA | Right | Right | 6' 5" | 200 lbs | - |
| Serrano, Gustavo | RF | Charleston Frasers | 30 | 05/19/2015 | Ahuatempan | MEX | Right | Right | 5' 11" | 190 lbs | - |
| Serrano, Luis | RF | Arizona Bay Lizards | 35 | 01/31/2010 | Pittsburgh | USA | Right | Right | 6' 2" | 200 lbs | - |
| Serrano, Manny | 3B | Kensington Wolfpack | 27 | 10/25/2017 | Burke | USA | Left | Right | 6' 2" | 205 lbs | - |
| Sexton, Jason | SP | Asheville Spitfires | 23 | 08/11/2021 | Burrillville | USA | Left | Left | 6' 6" | 200 lbs | - |
| Sheehan, Mark | CF | Mexico City Diablos Rojos | 23 | 03/17/2022 | Memphis | USA | Right | Right | 6' 2" | 190 lbs | - |
| Shepherd, Shane | RP | Asheville Spitfires | 24 | 08/18/2020 | Long Beach | USA | Right | Right | 6' 4" | 195 lbs | - |
| Silva, Chris | SP | Cleveland Spiders | 25 | 04/23/2020 | Las Cruces | USA | Right | Right | 6' 7" | 205 lbs | $300,000 |
| Silva, José | 3B | Free Agent | 30 | 11/20/2014 | Athens-Clarke County | USA | Right | Right | 6' 1" | 200 lbs | - |
| Simmons, Scott | 1B | Bowie Baysox | 28 | 12/25/2016 | Newark | USA | Right | Right | 6' 4" | 205 lbs | $300,000 |
| Smith, Chris | RP | Las Vegas Lightning | 29 | 10/06/2015 | Chesterfield | USA | Switch | Left | 6' 3" | 200 lbs | $300,000 |
| Smith, Richard | C | Free Agent | 29 | 10/04/2015 | Brooklyn | USA | Left | Right | 6' 5" | 215 lbs | - |
| Smith, Vaughn | SP | Asheville Spitfires | 25 | 05/08/2020 | Manhattan | USA | Right | Left | 6' 2" | 190 lbs | $300,000 |
| Snow, John | SP | Phoenix Seals | 27 | 07/01/2018 | Baytown | USA | Right | Right | 6' 2" | 190 lbs | $450,000 |
| So, Hun-ho | SP | Las Vegas Lightning | 28 | 04/20/2017 | Changwon | KOR | Right | Right | 6' 2" | 195 lbs | $300,000 |
| Solís, Joaquín | RP | Phoenix Seals | 33 | 01/16/2012 | Baní | DOM | Right | Right | 6' 4" | 210 lbs | - |
| Soriano, Nelson | RF | Bowie Baysox | 22 | 10/09/2022 | Moorhead | USA | Left | Left | 6' 6" | 205 lbs | $300,000 |
| Soto, Enrique | SS | Mexico City Diablos Rojos | 26 | 09/19/2018 | Montgomeryville | USA | Right | Right | 5' 10" | 185 lbs | - |
| Souza, Gabriel | C | Bowie Baysox | 30 | 02/19/2015 | Cardenas | CUB | Right | Right | 6' 1" | 200 lbs | - |
| Sparks, Shawn | RP | Arizona Bay Lizards | 36 | 11/19/2008 | Warren | USA | Switch | Right | 6' 4" | 205 lbs | - |
| Stafford, Patrick | RP | Arizona Bay Lizards | 28 | 07/17/2017 | East Saint Louis | USA | Right | Right | 5' 11" | 180 lbs | $300,000 |
| Stamps, Ray | 1B | Free Agent | 33 | 02/18/2012 | Tomball | USA | Left | Right | 6' 4" | 205 lbs | - |
| Stephens, Greg | RF | Free Agent | 26 | 08/20/2018 | New York | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stephenson, Bill | C | Detroit Wheels | 24 | 04/25/2021 | Fairfax | USA | Switch | Right | 5' 10" | 180 lbs | $300,000 |
| Stephenson, Colm | RP | Mexico City Diablos Rojos | 24 | 03/10/2021 | Fort Collins | USA | Right | Right | 6' 5" | 200 lbs | $300,000 |
| Sterling, Brendan | C | Free Agent | 29 | 10/30/2015 | Euclid | USA | Left | Right | 6' 0" | 200 lbs | - |
| Stewart, Shawn | RF | Free Agent | 28 | 06/19/2017 | Pittsburgh | USA | Switch | Right | 6' 4" | 205 lbs | - |
| Sugiura, Namboku | RP | Charleston Frasers | 24 | 07/11/2021 | Noboribetsu | JPN | Right | Right | 6' 0" | 175 lbs | - |
| Summers, Spencer | SP | Bowie Baysox | 32 | 12/09/2012 | Houston | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Susanti, Ijo | SP | Free Agent | 29 | 11/11/2015 | Vila | VAN | Left | Left | 6' 0" | 200 lbs | - |
| Sutherland, Clyde | RP | Detroit Wheels | 24 | 08/23/2020 | Bakersfield | USA | Right | Left | 6' 4" | 200 lbs | - |
| Suárez, Wilson | RP | Warminster Warriors | 29 | 04/26/2016 | Holguín | CUB | Switch | Right | 6' 0" | 200 lbs | - |
| Sánchez, Jorge | CF | Pukalani Paniolos | 24 | 04/02/2021 | Laconia | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Jorge | SP | Detroit Wheels | 25 | 08/08/2019 | Willingboro | USA | Right | Right | 6' 0" | 185 lbs | $300,000 |
| Sánchez, José | RP | Puget Sound Northmen | 24 | 02/27/2021 | Dallas | USA | Right | Right | 6' 3" | 210 lbs | - |
| Sánchez, Juan | RP | Free Agent | 26 | 12/29/2018 | Universal City | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Sánchez, Manuel | 3B | Free Agent | 26 | 08/17/2018 | Clinton | USA | Left | Right | 6' 4" | 200 lbs | - |
