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| Position | Top player | Team ranking | Top prospect | Organizational ranking | Overall ranking |
|---|---|---|---|---|---|
| Catchers | Christian Vazquez | 13th | Naysbel Marcano | 19th | 14th |
| First Basemen | Michael Chavis | 28th | Triston Casas | 17th | 28th |
| Second Basemen | Dustin Pedroia | 28th | Jeter Downs | 28th | 29th |
| Third Basemen | Rafael Devers | 8th | Brandon Howlett | 24th | 9th |
| Shortstops | Xander Bogaerts | 8th | Brainer Bonaci | 21st | 8th |
| Left Fielders | J.D. Martinez | 5th | Eduardo Lopez | 4th | 5th |
| Center Fielders | Kevin Pillar | 15th | Gilberto Jimenez | 7th | 13th |
| Right Fielders | Alex Verdugo | 6th | Nick Decker | 17th | 6th |
| Starting Pitchers | Chris Sale | 20th | Bryan Mata | 25th | 19th |
| Relievers | Colten Brewer | 23rd | Ryan Zeferjahn | 28th | 25th |
| Closers | Matt Barnes | 17th | Durbin Feltman | 17th | 13th |
