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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | H | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Ed Baxter# | 282 | 2038 | |
| 2 | Ed Baxter# | 274 | 2039 | |
| 3 | Jose Quintana | 273 | 2015 | |
| 4 | Cale Terry | 271 | 2028 | |
| 5 | Marcus Stroman | 270 | 2018 | |
| 6 | Shawn Schultz# | 269 | 2034 | |
| 7 | J.A. Happ | 268 | 2017 | |
| 8 | Rick Porcello | 267 | 2022 | |
| 9 | Corey Kluber | 265 | 2019 | |
| 10 | Rick Porcello | 263 | 2018 | |
| 11 | Rick Porcello | 262 | 2016 | |
| 11 | Jeremy Hellickson | 262 | 2020 | |
| 13 | Zach McAllister | 260 | 2016 | |
| 13 | Álex Martínez | 260 | 2028 | |
| 15 | Chad Tidwell | 259 | 2028 | |
| 16 | Mike Leake | 257 | 2018 | |
| 16 | Alex McClain | 257 | 2029 | |
| 16 | Aaron Nola | 257 | 2018 | |
| 19 | Adam Wainwright | 256 | 2019 | |
| 19 | Kwang-Hyun Kim | 256 | 2020 | |
| 21 | Chris Heston | 255 | 2018 | |
| 22 | Doug Jones | 253 | 2028 | |
| 23 | Juan Coutino | 252 | 2029 | |
| 23 | Ed Douglas# | 252 | 2036 | |
| 23 | Brett Anderson | 252 | 2017 | |
| 26 | Eric Ibáñez | 251 | 2028 | |
| 27 | Justin Verlander | 250 | 2016 | |
| 27 | Curt Pérez | 250 | 2035 | |
| 27 | Jeff Abbott# | 250 | 2039 | |
| 30 | Corey Kluber | 249 | 2018 | |
| 30 | Willie Anderson | 249 | 2026 | |
| 30 | Julio Teheran | 249 | 2019 | |
| 30 | Ty Blach | 249 | 2018 | |
| 30 | Jim Griffith# | 249 | 2039 | |
| 30 | Ed Solarana | 249 | 2028 | |
| 36 | Homer Bailey | 248 | 2018 | |
| 36 | Mario Patino | 248 | 2028 | |
| 36 | Cristo Gutiérrez# | 248 | 2027 | |
| 36 | Yen-ti Kao | 248 | 2022 | |
| 36 | Nolan Watson | 248 | 2029 | |
| 41 | Jose Quintana | 247 | 2019 | |
| 41 | Jaime Garcia | 247 | 2016 | |
| 41 | António Martínez | 247 | 2035 | |
| 44 | Zach Jones | 246 | 2026 | |
| 44 | Shelby Miller | 246 | 2026 | |
| 44 | Ron Duffy | 246 | 2028 | |
| 44 | Nathaniel Wigmore | 246 | 2029 | |
| 44 | Shawn Schultz# | 246 | 2035 | |
| 49 | Ed Baxter# | 245 | 2036 | |
| 49 | Mike Crawford# | 245 | 2037 | |
| 49 | Mike Leake | 245 | 2017 | |
| 49 | Alex McClain | 245 | 2033 | |
| 53 | Ed Solarana | 244 | 2026 | |
| 53 | Dave Bannatyne# | 244 | 2040 | |
| 55 | Curt Pérez | 243 | 2029 | |
| 55 | Matt Cain | 243 | 2018 | |
| 55 | Derek Holland | 243 | 2017 | |
| 55 | Chris Jordan# | 243 | 2037 | |
| 55 | Chris Ellis | 243 | 2028 | |
| 55 | Aurelio Benedettini | 243 | 2026 | |
| 55 | Kendall Graveman | 243 | 2016 | |
| 62 | Zack Greinke | 242 | 2015 | |
| 62 | Cristo Gutiérrez# | 242 | 2029 | |
| 62 | David García | 242 | 2020 | |
| 62 | John Danks | 242 | 2015 | |
| 66 | Braden Shipley | 241 | 2023 | |
| 66 | Ed Baxter# | 241 | 2029 | |
| 66 | Augusto Medina# | 241 | 2036 | |
| 66 | Tanner Roark | 241 | 2015 | |
| 66 | Brett Anderson | 241 | 2018 | |
| 66 | Jeff Abbott# | 241 | 2036 | |
| 66 | Joe Wilson# | 241 | 2041 | |
| 66 | Alfredo Baltaro | 241 | 2036 | |
| 66 | Ron Stonge# | 241 | 2037 | |
| 75 | Tim Lincecum | 240 | 2018 | |
| 75 | Aurelio Benedettini | 240 | 2027 | |
| 75 | Ty Blach | 240 | 2020 | |
| 75 | Ken McDonald# | 240 | 2036 | |
| 75 | Julio Teheran | 240 | 2021 | |
| 75 | Max Scherzer | 240 | 2016 | |
| 75 | Brett Anderson | 240 | 2019 | |
| 75 | Adam Wainwright | 240 | 2018 | |
| 75 | Thomas Szapucki | 240 | 2030 | |
| 84 | Jeff Samardzija | 239 | 2016 | |
| 84 | Andrew Heaney | 239 | 2018 | |
| 84 | Eddie Nix# | 239 | 2039 | |
| 84 | Kyle Hendricks | 239 | 2016 | |
| 84 | Homer Bailey | 239 | 2016 | |
| 89 | Tyler Matzek | 238 | 2015 | |
| 89 | Ed Solarana | 238 | 2027 | |
| 89 | Jordan Zimmermann | 238 | 2018 | |
| 89 | Manny Jiménez | 238 | 2034 | |
| 89 | Alex McClain | 238 | 2032 | |
| 89 | Mike Campbell | 238 | 2025 | |
| 89 | Nathaniel Wigmore | 238 | 2027 | |
| 89 | David García | 238 | 2021 | |
| 89 | Jeff Abbott# | 238 | 2034 | |
| 89 | Victor Payano | 238 | 2022 | |
| 89 | Junji Imai | 238 | 2038 | |
| 89 | Mike Minor | 238 | 2017 |
