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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salgado, Mario | 2B | Pulaski Yankees | 20 | 04/30/2013 | Floridablanca | COL | Right | Right | 6' 0" | 175 lbs | - |
| Sánchez, António | RP | Bluefield Blue Jays | 19 | 05/09/2014 | Barquisimeto | VEN | Switch | Right | 6' 0" | 180 lbs | - |
| Sánchez, Juan | SP | Pulaski Yankees | 20 | 04/12/2013 | La Vega | DOM | Right | Right | 6' 0" | 165 lbs | - |
| Sanderson, Jeff | 3B | Bristol Pirates | 22 | 02/27/2011 | Long Beach | USA | Right | Right | 6' 0" | 190 lbs | - |
| Saunders, Geoffrey | 3B | Kingsport Mets | 23 | 06/20/2010 | Philadelphia | USA | Right | Right | 6' 4" | 200 lbs | - |
| Schaaf, Eric | RP | Bristol Pirates | 22 | 02/03/2011 | Glendale | USA | Right | Right | 6' 2" | 195 lbs | - |
| Schulte, Bud | 1B | Bluefield Blue Jays | 19 | 06/30/2014 | Melvindale | USA | Right | Right | 6' 2" | 195 lbs | - |
| Seneca, Juan | 2B | Elizabethton Twins | 23 | 09/09/2010 | Caracas | VEN | Right | Right | 5' 10" | 175 lbs | - |
| Sergent, Eddie | C | Bristol Pirates | 23 | 03/31/2010 | Bee Ridge | USA | Switch | Right | 6' 0" | 200 lbs | - |
| Serna, Orlando | CF | Princeton Rays | 23 | 07/09/2010 | New York | USA | Right | Right | 6' 1" | 200 lbs | - |
| Seruya, Bernalldino | RP | Bluefield Blue Jays | 18 | 06/26/2015 | Punto Fijo | VEN | Switch | Right | 6' 1" | 175 lbs | - |
| Sevian, Khikanos | SS | Bristol Pirates | 24 | 07/05/2009 | North Atlanta | USA | Left | Right | 6' 0" | 190 lbs | - |
| Sewell, Lonnie | CF | Elizabethton Twins | 22 | 10/26/2011 | Zanesville | USA | Right | Right | 6' 1" | 195 lbs | - |
| Silva, César | LF | Bluefield Blue Jays | 19 | 05/08/2014 | Chivacoa | VEN | Left | Left | 6' 3" | 185 lbs | - |
| Silva, José | 1B | Greeneville Reds | 22 | 08/09/2011 | Petare | VEN | Left | Left | 6' 3" | 205 lbs | - |
| Silver, Andy | RP | Burlington Royals | 19 | 03/01/2014 | Forney | USA | Right | Right | 5' 11" | 170 lbs | - |
| Smith, Clarence | C | Johnson City Cardinals | 23 | 10/18/2010 | Los Angeles | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Smith, Eric | C | Elizabethton Twins | 23 | 05/15/2010 | Watsonville | USA | Right | Right | 6' 2" | 205 lbs | - |
| Smith, Greg | 3B | Burlington Royals | 32 | 08/04/2001 | Ankeny | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Marlon | CL | Danville Braves | 23 | 11/14/2010 | East Wenatchee Bench | USA | Left | Left | 5' 11" | 175 lbs | - |
| Sosa, Gregorio | SP | Kingsport Mets | 23 | 02/17/2010 | Santo Domingo | DOM | Right | Right | 5' 11" | 180 lbs | - |
| Souza, Juan | C | Bluefield Blue Jays | 19 | 09/18/2014 | Valencia | VEN | Right | Right | 5' 10" | 175 lbs | - |
| Stephens, Ben | C | Princeton Rays | 23 | 05/13/2010 | Miami Lakes | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stewart, Bob | RP | Burlington Royals | 19 | 05/11/2014 | San Francisco | USA | Right | Right | 6' 4" | 180 lbs | - |
| Stewart, Jon | 3B | Princeton Rays | 25 | 10/15/2008 | Plainfield | USA | Left | Right | 5' 11" | 200 lbs | - |
