| # | Name | Team | Opp | Date | Score | IP | R | H | HR | BB | K | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | David Alvarez | COL | STL | April 16, 2000 | 10-0 | 9.0 | 0 | 3 | 0 | 2 | 12 | 96 |
| 2 | Marco Benitez | SEA | TB | May 19, 2000 | 1-0 | 9.0 | 0 | 2 | 0 | 1 | 7 | 95 |
| 3 | Marco Benitez | SEA | CLE | April 26, 2000 | 6-0 | 9.0 | 0 | 4 | 0 | 0 | 8 | 94 |
| 4 | Marco Benitez | SEA | OAK | May 13, 2000 | 5-0 | 9.0 | 0 | 2 | 0 | 3 | 10 | 94 |
| 5 | Curt Schilling | OAK | DET | April 3, 2000 | 2-1 | 9.0 | 1 | 4 | 0 | 1 | 13 | 94 |
| 6 | Ed Martel | TOR | ANA | April 19, 2000 | 4-0 | 8.2 | 0 | 3 | 0 | 1 | 9 | 93 |
| 7 | Matt Murray | NYM | LAD | April 8, 2000 | 7-0 | 9.0 | 0 | 1 | 0 | 3 | 7 | 93 |
| 8 | Javier Vazquez | SF | ATL | April 8, 2000 | 15-0 | 9.0 | 0 | 2 | 0 | 2 | 7 | 93 |
| 9 | Jeff Bawlson | KC | MIN | April 9, 2000 | 11-0 | 9.0 | 0 | 2 | 0 | 1 | 4 | 92 |
| 10 | J J Thobe | PHI | ARI | April 26, 2000 | 1-0 | 8.2 | 0 | 1 | 0 | 3 | 8 | 92 |
| 11 | Matt Murray | NYM | COL | May 18, 2000 | 12-0 | 9.0 | 0 | 3 | 0 | 3 | 9 | 91 |
| 12 | Mike Magnante | SF | COL | May 12, 2000 | 4-0 | 9.0 | 0 | 3 | 0 | 3 | 8 | 90 |
| 13 | Mike Mussina | MLW | STL | April 25, 2000 | 13-0 | 9.0 | 0 | 3 | 0 | 3 | 8 | 90 |
| 14 | Greg Maddux | NYM | SD | April 3, 2000 | 1-0 | 9.0 | 0 | 2 | 0 | 3 | 5 | 89 |
| 15 | Jaret Wright | CIN | NYM | April 26, 2000 | 4-0 | 9.0 | 0 | 5 | 0 | 1 | 7 | 89 |
| 16 | Tom Gordon | HOU | MLW | May 1, 2000 | 2-1 | 8.2 | 1 | 3 | 0 | 2 | 9 | 88 |
| 17 | Chris Bosio | CHC | LAD | May 18, 2000 | 8-1 | 9.0 | 1 | 4 | 0 | 0 | 5 | 88 |
| 18 | Denny Neagle | ARI | PIT | April 7, 2000 | 4-0 | 8.2 | 0 | 4 | 0 | 1 | 6 | 88 |
| 19 | Mike Mussina | MLW | ATL | April 14, 2000 | 6-1 | 9.0 | 1 | 3 | 0 | 2 | 7 | 88 |
| 20 | Salomon Torres | TOR | ANA | April 17, 2000 | 4-1 | 9.0 | 1 | 3 | 0 | 2 | 7 | 88 |
| 21 | Bill Sandoval | HOU | LAD | April 17, 2000 | 19-0 | 9.0 | 0 | 2 | 0 | 4 | 6 | 88 |
| 22 | Bill Sandoval | HOU | CHC | May 4, 2000 | 6-0 | 9.0 | 0 | 5 | 0 | 1 | 6 | 88 |
| 23 | Lupe Villanueva | CIN | SD | May 10, 2000 | 14-0 | 8.1 | 0 | 3 | 0 | 2 | 8 | 88 |
| 24 | Michael Costello | CWS | ANA | April 14, 2000 | 9-1 | 9.0 | 1 | 4 | 0 | 2 | 8 | 87 |
| 25 | Greg Swindell | MIN | DET | May 6, 2000 | 14-1 | 9.0 | 1 | 6 | 0 | 1 | 10 | 87 |
| 26 | John Burkett | BOS | DET | May 20, 2000 | 8-0 | 8.0 | 0 | 4 | 0 | 1 | 9 | 87 |
| 27 | Cesar Maldonado | OAK | TOR | April 26, 2000 | 8-0 | 9.0 | 0 | 4 | 0 | 2 | 5 | 87 |
| 28 | Mike Mussina | MLW | HOU | April 30, 2000 | 3-0 | 8.1 | 0 | 2 | 0 | 3 | 7 | 87 |
| 29 | J J Thobe | PHI | CIN | May 2, 2000 | 6-0 | 9.0 | 0 | 3 | 0 | 4 | 7 | 87 |
| 30 | Juan Contreras | STL | PIT | May 19, 2000 | 5-1 | 8.1 | 1 | 3 | 0 | 2 | 10 | 87 |