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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Brien, R.J. | LF | Atlanta Braves | 40 | 04/18/2012 | Danbury | USA | Left | Left | 6' 2" | 200 lbs | $2,500,000 |
| O'Connor, Troy | SP | Chicago White Sox | 24 | 01/13/2028 | Sydney | AUS | Right | Right | 6' 2" | 190 lbs | $675,000 |
| Oakes, Eric | RP | Chicago Cubs | 31 | 10/30/2020 | Mitchellville | USA | Right | Right | 6' 5" | 195 lbs | $9,000,000 |
| Ocampo, Ignacio | LF | St. Louis Cardinals | 23 | 01/15/2029 | Fajardo | PUR | Left | Left | 6' 2" | 180 lbs | $675,000 |
| Ogle, Nick | 1B | Free Agent | 29 | 08/28/2022 | Flora | USA | Right | Right | 6' 4" | 200 lbs | - |
| Ohmer, Austin | CF | Montreal Expos | 29 | 07/17/2022 | St. Joseph | USA | Left | Right | 5' 10" | 205 lbs | $22,000,000 |
| Ohnn, Young-kwang | C | Free Agent | 34 | 05/04/2018 | Incheon | KOR | Right | Right | 6' 0" | 200 lbs | - |
| Okamoto, Kensaku | SP | Texas Rangers | 17 | 10/23/2034 | Sapporo | JPN | Left | Right | 6' 2" | 180 lbs | - |
| Olivas, Edwin | 3B | Houston Astros | 16 | 09/20/2035 | Campechuela | CUB | Right | Right | 6' 3" | 190 lbs | - |
| Olvera, Sergio | 1B | Oakland Athletics | 18 | 10/11/2033 | Holguín | CUB | Switch | Right | 6' 4" | 200 lbs | - |
| Ontiveros, Vinny | RF | Pittsburgh Pirates | 17 | 01/23/2035 | Santiago de Cuba | CUB | Left | Left | 6' 1" | 175 lbs | - |
| Orosco, Omar | RP | Philadelphia Phillies | 28 | 05/01/2024 | Calexico | USA | Right | Right | 6' 4" | 205 lbs | $1,000,000 |
| Orozco, Dave | RF | Oakland Athletics | 16 | 08/16/2035 | Guantanamo | CUB | Left | Left | 6' 0" | 180 lbs | - |
| Orphan, Matthew | SP | Kansas City Royals | 28 | 02/13/2024 | Hillsborough | USA | Right | Right | 6' 2" | 200 lbs | $675,000 |
| Ortiz, Danny | RF | Pittsburgh Pirates | 17 | 08/21/2034 | Xalapa | MEX | Left | Left | 6' 1" | 185 lbs | - |
| Ortiz, Terciero | 1B | Houston Astros | 23 | 11/24/2028 | Ceres | USA | Switch | Right | 6' 3" | 205 lbs | $675,000 |
| Osgood, Mike | RP | Arizona Diamondbacks | 26 | 11/01/2025 | Detroit | USA | Left | Right | 6' 5" | 200 lbs | $675,000 |
| Ovens-Toots, Kevin | SP | Kansas City Royals | 31 | 05/27/2021 | Lake Charles | USA | Right | Right | 6' 1" | 200 lbs | $21,000,000 |
| Overbeek, Jack | SP | Houston Astros | 36 | 03/13/2016 | Tytsjerksteradiel | NED | Right | Right | 6' 6" | 200 lbs | $1,600,000 |
| Overlie, Justin | RP | New York Mets | 28 | 02/20/2024 | Salt Lake City | USA | Right | Right | 5' 11" | 190 lbs | $2,369,400 |
| Owens, John | RP | Colorado Rockies | 31 | 07/21/2020 | Norristown | USA | Right | Right | 6' 3" | 200 lbs | $2,400,000 |
| Oxenrider, Alan | 1B | Free Agent | 38 | 11/14/2013 | Lyman | USA | Right | Right | 6' 2" | 200 lbs | - |
