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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Luis | RP | Lakeland Flying Tigers | 22 | 10/03/2008 | La Romana | DOM | Switch | Right | 6' 3" | 200 lbs | - |
| Sanchez, Roberto | RF | Free Agent | 27 | 03/07/2003 | Guarenas | VEN | Left | Left | 6' 1" | 195 lbs | - |
| Sanchez, Willie | 2B | Fort Myers Mighty Mussels | 22 | 03/26/2008 | Villa Bisonó | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sanfilippo, Chris | SS | Fort Myers Mighty Mussels | 23 | 10/01/2007 | Davenport | USA | Right | Right | 6' 4" | 200 lbs | - |
| Santa Cruz, Luis | CF | Fort Myers Mighty Mussels | 20 | 01/02/2010 | Candelaria | PUR | Right | Right | 6' 1" | 180 lbs | - |
| Santamaria, Jorge | 3B | Lakeland Flying Tigers | 21 | 10/23/2009 | Hyde | USA | Right | Right | 6' 2" | 185 lbs | - |
| Santoscoy, Jim | SS | Tampa Tarpons | 23 | 04/19/2007 | Bowling Green | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sazo, Jorge | C | St. Lucie Mets | 22 | 08/12/2008 | Yamasa | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Schaller, Jeff | 3B | Jupiter Hammerheads | 22 | 05/31/2008 | Modesto | USA | Left | Right | 6' 2" | 205 lbs | - |
| Schillinger, Doug | RP | Daytona Tortugas | 19 | 05/29/2011 | San Antonio | USA | Right | Right | 5' 10" | 155 lbs | - |
| Schreiner, Zach | SP | Jupiter Hammerheads | 23 | 09/26/2007 | Coral Springs | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Shaheen, Mike | CF | Daytona Tortugas | 18 | 11/03/2012 | Astoria | USA | Left | Right | 6' 6" | 195 lbs | - |
| Shoulders, T.J. | CF | Fort Myers Mighty Mussels | 20 | 06/09/2010 | Gillette | USA | Right | Right | 6' 4" | 180 lbs | - |
| Silva, Nicolas | RP | Lakeland Flying Tigers | 20 | 11/10/2010 | Santo Domingo | DOM | Right | Right | 6' 7" | 200 lbs | - |
| Simon, Nyjel | C | Dunedin Blue Jays | 21 | 01/04/2009 | Sugar Hill | USA | Left | Right | 6' 2" | 205 lbs | - |
| Singer, Phil | 3B | Jupiter Hammerheads | 30 | 08/01/2000 | McHenry | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Snodgrass, Danny | SS | Daytona Tortugas | 19 | 05/29/2011 | Santa Rosa | USA | Right | Right | 6' 0" | 170 lbs | - |
| Solis, Danny | SP | Dunedin Blue Jays | 23 | 08/13/2007 | Greenfield | USA | Left | Left | 5' 10" | 185 lbs | - |
| Soto, Alex | C | Palm Beach Cardinals | 20 | 08/28/2010 | Barquisimeto | VEN | Right | Right | 6' 0" | 185 lbs | - |
| Steiner, Danny | C | Dunedin Blue Jays | 24 | 10/01/2006 | Longview | USA | Right | Right | 6' 6" | 240 lbs | - |
| Strong, Darius | CF | Tampa Tarpons | 23 | 12/12/2006 | O'Fallon | USA | Left | Left | 6' 2" | 195 lbs | - |
