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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Edgar, Lewie | C | Free Agent | 34 | 12/18/2016 | Sandusky | USA | Right | Right | 5' 10" | 200 lbs | - |
| Edgrien, Víctor | SS | Los Angeles Greyhounds | 18 | 12/12/2032 | Havana | CUB | Right | Right | 6' 3" | 180 lbs | - |
| Elder, Jonathan | 1B | New Orleans Gators | 33 | 03/01/2018 | Mount Pleasant | USA | Right | Right | 6' 0" | 185 lbs | $2,500,000 |
| Encarnación, Luis Antonio | RP | Colorado Anasazi | 28 | 09/22/2022 | Kingman | USA | Right | Right | 6' 1" | 200 lbs | $900,000 |
| Endo, Takamasa | RP | Los Angeles Greyhounds | 33 | 11/21/2017 | Sendai | JPN | Right | Right | 6' 0" | 205 lbs | $900,000 |
| Er, Zhi-jan | SP | San Francisco Bullets | 17 | 11/14/2033 | Summerside | CAN | Left | Right | 6' 5" | 195 lbs | - |
| Escalante, Jorge | C | Philadelphia Pride | 33 | 05/12/2018 | Durango | MEX | Right | Right | 6' 0" | 200 lbs | $3,500,000 |
| Escamilla, Sergio | 2B | Houston Hurricane | 29 | 09/06/2021 | Baracoa | CUB | Right | Right | 6' 0" | 190 lbs | $14,375,000 |
| Escobedo, Sergio | 3B | Providence Grays | 30 | 01/15/2021 | Pedernales | DOM | Left | Right | 6' 4" | 200 lbs | $1,890,000 |
| Espinho, Mende | C | Los Angeles Greyhounds | 25 | 01/14/2026 | Rio de Janeiro | BRA | Right | Right | 6' 6" | 210 lbs | $500,000 |
| Espinosa, José | SP | Los Angeles Greyhounds | 18 | 11/16/2032 | Baragua | CUB | Left | Right | 6' 1" | 180 lbs | - |
| Espinoza, Cristián | SP | Miami Manatees | 30 | 01/20/2021 | Smith Mills | USA | Right | Right | 6' 0" | 200 lbs | $900,000 |
| Espinoza, Luis | 1B | Miami Manatees | 26 | 03/04/2025 | San José de Ocoa | DOM | Left | Left | 6' 4" | 200 lbs | $500,000 |
| Estrada, António | SS | Beaverton Bulldogs | 31 | 10/06/2019 | Glen Allen | USA | Right | Right | 6' 4" | 195 lbs | $1,250,000 |
| Estrada, José | C | New Jersey Zombies | 19 | 01/28/2032 | Uruapan | MEX | Switch | Right | 6' 1" | 180 lbs | - |
| Estrada, Juan | LF | Beaverton Bulldogs | 17 | 07/27/2033 | Bayamón | PUR | Right | Right | 6' 2" | 185 lbs | - |
| Estrada, Ángelo | SP | Los Angeles Greyhounds | 18 | 05/06/2033 | Barahona | DOM | Right | Right | 6' 1" | 180 lbs | - |
