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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saito, Osamu | SP | Beaverton Bulldogs | 18 | 02/01/2033 | Oita | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Sakaguchi, Takafumi | 3B | New Orleans Gators | 17 | 10/08/2033 | Okazaki | JPN | Right | Right | 6' 1" | 180 lbs | - |
| Sakai, Shinzo | CF | New Jersey Zombies | 19 | 05/26/2032 | Kurashiki | JPN | Right | Left | 6' 3" | 180 lbs | - |
| Salazar, Jorge | SP | Colorado Anasazi | 19 | 04/01/2032 | Valencia | VEN | Left | Left | 6' 5" | 200 lbs | - |
| Salazar, José | SP | Los Angeles Greyhounds | 31 | 05/01/2020 | Acajete | MEX | Left | Left | 6' 1" | 190 lbs | $500,000 |
| Salcido, David | SP | Colorado Anasazi | 19 | 04/03/2032 | Santo Domingo | DOM | Switch | Right | 6' 0" | 175 lbs | - |
| Saldaña, David | C | St. Louis Pioneers | 16 | 08/11/2034 | San Pedro de Macorís | DOM | Left | Right | 6' 3" | 195 lbs | - |
| Samurakami, Takejiro | C | Toronto Maple Leafs | 26 | 05/04/2025 | Tokorozawa | JPN | Switch | Right | 6' 2" | 200 lbs | $500,000 |
| Sanders, Cliff | RF | Houston Hurricane | 23 | 08/06/2027 | Owensboro | USA | Right | Right | 6' 3" | 200 lbs | $500,000 |
| Sandoval, Pepe | SS | Colorado Anasazi | 25 | 09/10/2025 | Brooklyn | USA | Switch | Right | 6' 3" | 200 lbs | $500,000 |
| Santana, Ernesto | RP | Free Agent | 34 | 04/28/2017 | Augusta-Richmond | USA | Left | Left | 6' 3" | 195 lbs | - |
| Sanu, Sadao | SP | Atlanta Whale Sharks | 19 | 03/15/2032 | Sendai | JPN | Right | Right | 6' 4" | 190 lbs | - |
| Sasaki, Yujiro | RP | Free Agent | 27 | 10/18/2023 | Kosugi | JPN | Left | Left | 6' 3" | 215 lbs | - |
| Sato, Haruki | SP | Los Angeles Greyhounds | 17 | 02/24/2034 | Kagoshima | JPN | Switch | Right | 6' 5" | 195 lbs | - |
| Sato, Tadaaki | 1B | Philadelphia Pride | 18 | 11/08/2032 | Niihama | JPN | Left | Right | 5' 9" | 160 lbs | - |
| Saucedo, Juan | SP | Free Agent | 18 | 07/10/2032 | Coatepeque | GUA | Left | Left | 6' 1" | 175 lbs | - |
| Saunders, Dan | RP | Colorado Anasazi | 37 | 12/18/2013 | Camden | USA | Right | Right | 6' 1" | 205 lbs | $1,400,000 |
| Savoie, Leland | 1B | Miami Manatees | 17 | 07/02/2034 | Gibsons | CAN | Left | Left | 6' 2" | 195 lbs | - |
| Seaman, Brent | SP | Houston Hurricane | 25 | 03/06/2026 | Toronto | CAN | Left | Left | 6' 1" | 195 lbs | $500,000 |
| Serna, Jorge | LF | Chicago Rage | 26 | 08/30/2024 | Brookline | USA | Left | Left | 6' 3" | 205 lbs | $800,000 |
| Serrano, Héctor | SP | San Francisco Bullets | 16 | 10/30/2034 | Querétaro | MEX | Right | Right | 6' 2" | 175 lbs | - |
| Serres, Jean-Claude | RF | New Orleans Gators | 16 | 07/27/2034 | Trélissac | FRA | Left | Left | 6' 6" | 195 lbs | - |
| Setas, Juan Carlos | SP | New Orleans Gators | 28 | 05/26/2023 | Ciudad Guayana | VEN | Left | Right | 6' 1" | 195 lbs | $3,200,000 |
| Sexton, Eric | 3B | Houston Hurricane | 30 | 05/20/2021 | Ewa Gentry | USA | Right | Right | 6' 0" | 205 lbs | $1,500,000 |
| Seánez, José | DH | New Orleans Gators | 32 | 09/30/2018 | Crystal Lake | USA | Left | Right | 6' 6" | 200 lbs | $2,750,000 |
| Shanks, Bobby | 3B | Chicago Rage | 27 | 09/28/2023 | Boise | USA | Switch | Right | 6' 0" | 200 lbs | $500,000 |
| Shao, Lien-ying | SP | New Orleans Gators | 32 | 05/05/2019 | Puli | TPE | Left | Left | 6' 1" | 200 lbs | $1,200,000 |
| Sharkey, Ben | SP | Philadelphia Pride | 19 | 12/20/2031 | Calgary | CAN | Right | Right | 6' 2" | 185 lbs | - |
| Shaw, Dave | RP | New Jersey Zombies | 31 | 05/24/2020 | Ocean Springs | USA | Right | Right | 5' 10" | 175 lbs | $500,000 |
| Shen, Kai-xi | SP | Colorado Anasazi | 19 | 09/11/2031 | Nanchang | CHN | Right | Right | 6' 2" | 185 lbs | - |
| Shields, Brad | RF | Los Angeles Greyhounds | 31 | 10/10/2019 | El Dorado Hills | USA | Left | Left | 6' 0" | 185 lbs | $1,020,000 |
| Shimizu, Soetsu | SP | Atlanta Whale Sharks | 19 | 03/28/2032 | Hirosaki | JPN | Right | Right | 5' 11" | 160 lbs | - |
| Shirai, Kimitada | CF | Free Agent | 16 | 02/09/2035 | Sagamihara | JPN | Right | Right | 6' 1" | 165 lbs | - |
| Short, Brad | RF | Dakota Rattlers | 29 | 08/28/2021 | Los Angeles | USA | Left | Left | 6' 1" | 200 lbs | $500,000 |
| Silva, César | 1B | Philadelphia Pride | 17 | 02/25/2034 | Santo Domingo | DOM | Right | Right | 6' 5" | 205 lbs | - |
| Silva, Pancho | LF | San Francisco Bullets | 35 | 05/06/2016 | Santo Domingo | DOM | Right | Right | 6' 2" | 205 lbs | $1,200,000 |
| Simmons, Don | RP | New Jersey Zombies | 29 | 10/10/2021 | Brooklyn | USA | Right | Right | 6' 2" | 205 lbs | $500,000 |
| Simpson, Mike | RP | Colorado Anasazi | 34 | 01/09/2017 | Belleville | USA | Right | Right | 6' 2" | 200 lbs | $1,800,000 |
| Slater, Norbert | RP | Toronto Maple Leafs | 25 | 06/17/2026 | Santa Paula | USA | Right | Right | 6' 1" | 185 lbs | $500,000 |
| Smith, Jim | 3B | Free Agent | 33 | 06/20/2018 | Manhattan | USA | Left | Right | 6' 0" | 200 lbs | - |
| Smith, Ned | SP | Colorado Anasazi | 27 | 01/20/2024 | Bridgewater | USA | Right | Right | 6' 4" | 200 lbs | $900,000 |
| Smith, Trey | 2B | St. Louis Pioneers | 25 | 05/20/2026 | Los Angeles | USA | Left | Right | 6' 3" | 200 lbs | $4,880,000 |
| Smith, Ty | RP | St. Louis Pioneers | 31 | 03/19/2020 | Tacoma | USA | Right | Right | 6' 3" | 200 lbs | $2,127,534 |
| Snyder, Hugh | RF | New Jersey Zombies | 25 | 08/19/2025 | Seaside | USA | Left | Left | 6' 4" | 200 lbs | $500,000 |
| Solís, Juan | SS | Beaverton Bulldogs | 28 | 06/11/2023 | Puntarenas | CRC | Right | Right | 6' 1" | 200 lbs | $4,750,000 |
| Soriano, José | 3B | Chicago Rage | 18 | 09/01/2032 | Holguín | CUB | Right | Right | 6' 1" | 180 lbs | - |
| Soriano, Álex | CF | Colorado Anasazi | 30 | 11/06/2020 | Santa Ana | USA | Right | Right | 6' 4" | 200 lbs | $2,175,000 |
| Sosa, Jorge | C | Atlanta Whale Sharks | 28 | 04/25/2023 | Somoto | NCA | Right | Right | 5' 10" | 200 lbs | $500,000 |
| Sosa, Juan | SP | San Francisco Bullets | 17 | 06/12/2034 | Santo Domingo | DOM | Right | Right | 6' 7" | 200 lbs | - |
| Sosa, Pancho | 2B | Washington Palace Nine | 18 | 01/22/2033 | Mayagüez | PUR | Right | Right | 6' 1" | 175 lbs | - |
| Soto, Alfredo | SP | Houston Hurricane | 19 | 12/14/2031 | Puebla | MEX | Right | Right | 6' 1" | 170 lbs | - |
| Soto, José | SP | New Orleans Gators | 17 | 03/26/2034 | Panama | PAN | Right | Right | 6' 1" | 170 lbs | - |
| Stahlman, Steve | CF | Chicago Rage | 17 | 02/08/2034 | Vancouver | CAN | Left | Left | 6' 2" | 170 lbs | - |
| Stanely, Micah | C | Providence Grays | 27 | 04/06/2024 | Northwoods | USA | Right | Right | 5' 10" | 200 lbs | $500,000 |
| Stodge, Bobby | SP | Dakota Rattlers | 32 | 05/02/2019 | Lexington | USA | Switch | Right | 6' 5" | 200 lbs | $15,800,000 |
| Suitani, Seishiro | RP | Beaverton Bulldogs | 30 | 05/04/2021 | Kyoto | JPN | Right | Right | 6' 1" | 195 lbs | $3,000,000 |
| Sullivan, Joe | SP | Colorado Anasazi | 25 | 08/26/2025 | Oregon City | USA | Right | Right | 6' 6" | 205 lbs | $500,000 |
| Sullivan, Kevin | SP | Providence Grays | 29 | 11/07/2021 | Hillsboro | USA | Right | Right | 6' 0" | 200 lbs | $3,220,000 |
| Sutton, Tommy | SP | Houston Hurricane | 19 | 09/17/2031 | San Juan | PUR | Left | Left | 6' 1" | 175 lbs | - |
| Suzuki, Katsuyoshi | SP | Atlanta Whale Sharks | 18 | 12/12/2032 | Sagamihara | JPN | Left | Left | 6' 5" | 185 lbs | - |
| Swanson, Jeff | LF | Washington Palace Nine | 26 | 05/30/2025 | Beverly | USA | Right | Left | 6' 3" | 200 lbs | $945,000 |
| Sánchez, António | SP | Philadelphia Pride | 17 | 03/04/2034 | Baní | DOM | Left | Left | 6' 5" | 190 lbs | - |
| Sánchez, Edgardo | SP | Atlanta Whale Sharks | 25 | 03/12/2026 | Manhattan | USA | Switch | Right | 6' 3" | 195 lbs | $500,000 |
| Sánchez, José | SP | Houston Hurricane | 18 | 05/13/2033 | Santo Domingo | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sánchez, José | CF | New Jersey Zombies | 19 | 08/26/2031 | San Juan | PUR | Right | Right | 6' 5" | 195 lbs | - |
| Sánchez, José | LF | Free Agent | 35 | 05/21/2016 | Lake Ronkonkoma | USA | Right | Right | 5' 10" | 195 lbs | - |
| Sánchez, Manny | SP | Chicago Rage | 29 | 09/15/2021 | Nuevo Laredo | MEX | Right | Right | 6' 2" | 195 lbs | $5,250,000 |
| Sánchez, Rubén | C | Free Agent | 16 | 06/01/2035 | Santo Domingo | DOM | Switch | Right | 6' 1" | 170 lbs | - |
