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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Luis | RP | Memphis Redbirds | 29 | 07/24/2042 | Guatemala | GUA | Right | Right | 6' 7" | 200 lbs | $500,000 |
| Salazar, Jesús | C | Oklahoma City RedHawks | 30 | 10/12/2040 | Mexico City | MEX | Right | Right | 6' 5" | 195 lbs | - |
| Sanders, Bob | SS | Sacramento River Cats | 23 | 09/21/2047 | Lake City | USA | Switch | Right | 5' 11" | 180 lbs | - |
| Sanders, Ken | RP | Colorado Springs Sky Sox | 23 | 07/10/2048 | Russellville | USA | Right | Right | 6' 1" | 180 lbs | - |
| Sanders, Mitchell | LF | Tacoma Rainiers | 24 | 09/27/2046 | Brownsville | USA | Left | Left | 6' 4" | 200 lbs | - |
| Santana, Víctor | SS | Portland Beavers | 24 | 05/22/2047 | Managua | NCA | Right | Right | 6' 3" | 190 lbs | $500,000 |
| Santos, Raúl | SP | Oklahoma City RedHawks | 30 | 06/11/2041 | Santiago de Cuba | CUB | Right | Right | 6' 1" | 195 lbs | $500,000 |
| Santos, Tomás | SS | Memphis Redbirds | 26 | 01/12/2045 | San Rafael | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sarmie, Rob | SP | Oklahoma City RedHawks | 29 | 04/25/2042 | Weehawken | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sasaki, Muneyaki | RF | Free Agent | 27 | 11/24/2043 | Kitakyushu | JPN | Left | Left | 6' 4" | 205 lbs | - |
| Saucedo, Juan Carlos | SP | Free Agent | 31 | 03/17/2040 | Quila | MEX | Right | Right | 6' 4" | 200 lbs | - |
| Saunders, David | SP | Colorado Springs Sky Sox | 24 | 05/17/2047 | Cayucos | USA | Right | Right | 6' 0" | 195 lbs | - |
| Schmidt, Chet | SP | Albuquerque Isotopes | 30 | 11/02/2040 | Temecula | USA | Left | Left | 5' 9" | 190 lbs | - |
| Sears, Jason | RP | Portland Beavers | 26 | 08/06/2045 | Montgomery Village | USA | Right | Right | 6' 2" | 200 lbs | - |
| Segundo, Tilmão | SP | Free Agent | 33 | 03/17/2038 | Natal | BRA | Left | Left | 6' 8" | 195 lbs | - |
| Seki, Ichiro | DH | New Orleans Zephyrs | 28 | 04/13/2043 | Kobe | JPN | Left | Left | 6' 6" | 200 lbs | - |
| Seymour, Del | 1B | El Paso Chihuahuas | 34 | 07/11/2037 | Mount Pleasant | USA | Right | Right | 6' 4" | 200 lbs | - |
| Shaffer, Don | LF | Colorado Springs Sky Sox | 26 | 10/11/2044 | Rocky River | USA | Right | Right | 6' 7" | 200 lbs | - |
| Shaw, Joseph | RP | Nashville Sounds | 31 | 01/22/2040 | Houston | USA | Right | Right | 6' 0" | 200 lbs | $1,050,000 |
| Shee, Brandon | CF | Free Agent | 33 | 04/23/2038 | Weddington | USA | Left | Right | 6' 1" | 200 lbs | - |
| Shibutani, Kosho | SS | Salt Lake Bees | 30 | 06/18/2041 | Kakogawa | JPN | Right | Right | 6' 4" | 200 lbs | $500,000 |
| Silva, José | LF | Las Vegas 51s | 25 | 04/29/2046 | Carolina | PUR | Right | Left | 6' 3" | 200 lbs | - |
| Simms, Ben | SP | Tucson Padres | 25 | 05/07/2046 | Laval | CAN | Right | Right | 6' 3" | 200 lbs | $500,000 |
| Sims, Matt | SP | Portland Beavers | 21 | 09/07/2049 | Dallas | USA | Left | Left | 6' 2" | 180 lbs | - |
| Slee, Roger | SP | Omaha Storm Chasers | 25 | 08/15/2045 | Minneapolis | USA | Right | Left | 6' 0" | 200 lbs | - |
| Smith, Chris | SP | Tacoma Rainiers | 29 | 11/16/2041 | Manhattan | USA | Switch | Left | 6' 2" | 200 lbs | $2,200,000 |
| Smith, Woody | RP | Omaha Storm Chasers | 26 | 06/22/2045 | Beverly Hills | USA | Right | Right | 6' 0" | 195 lbs | - |
| Snyder, Robert | SP | Free Agent | 37 | 04/28/2034 | Normandy | USA | Right | Right | 6' 4" | 200 lbs | - |
| Song, Hyun-ook | RP | Las Vegas 51s | 23 | 01/26/2048 | Chinju | KOR | Right | Right | 6' 4" | 185 lbs | - |
| Soranzo, Gavino | RP | Round Rock Express | 32 | 06/03/2039 | Milan | ITA | Right | Right | 5' 11" | 195 lbs | - |
| Soto, José | 1B | Fresno Grizzlies | 33 | 05/27/2038 | Tula de Allende | MEX | Left | Right | 6' 3" | 200 lbs | - |
| Soto, Pablo | RP | Sacramento River Cats | 31 | 09/15/2039 | Duvergé | DOM | Left | Right | 6' 5" | 200 lbs | $700,000 |
| Soto, Ricardo | SP | El Paso Chihuahuas | 32 | 02/08/2039 | Varadero | CUB | Right | Right | 6' 4" | 200 lbs | - |
| Souza, Juan | 2B | Oklahoma City RedHawks | 26 | 05/05/2045 | Twin Lakes | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Souza, Mario | LF | Free Agent | 30 | 03/06/2041 | Murrieta | USA | Left | Left | 6' 1" | 195 lbs | - |
| Stafford, Allen | 3B | Free Agent | 26 | 08/08/2045 | Lindsay | USA | Right | Right | 5' 10" | 200 lbs | - |
| Stephens, Zach | C | Colorado Springs Sky Sox | 23 | 05/30/2048 | Hamilton | CAN | Left | Right | 6' 3" | 210 lbs | - |
| Stevens, David | 2B | Memphis Redbirds | 25 | 10/04/2045 | Indianapolis | USA | Right | Right | 6' 1" | 190 lbs | $500,000 |
| Stevenson, Peter | RP | Iowa Cubs | 26 | 07/22/2045 | Concord | USA | Right | Right | 6' 2" | 200 lbs | $500,000 |
| Stewart, Carl | 2B | Las Vegas 51s | 27 | 10/19/2043 | North Creek | USA | Right | Right | 6' 0" | 200 lbs | $500,000 |
| Stinson, Leon | RP | Tucson Padres | 25 | 07/19/2046 | Brooklyn | USA | Left | Left | 6' 2" | 200 lbs | - |
| Stobart, Don | SP | Tucson Padres | 27 | 12/17/2043 | Pharr | USA | Right | Right | 6' 0" | 185 lbs | $500,000 |
| Sullivan, Gregg | SP | Free Agent | 30 | 01/05/2041 | Los Angeles | USA | Left | Right | 6' 0" | 195 lbs | - |
| Sumpter, Troy | SP | Portland Beavers | 26 | 09/01/2044 | Davenport | USA | Right | Right | 6' 8" | 205 lbs | - |
| Sun, Bing-zhang | LF | Nashville Sounds | 25 | 06/16/2046 | Tali | TPE | Left | Left | 6' 1" | 195 lbs | $500,000 |
| Sutherland, Dave | RP | Iowa Cubs | 24 | 01/25/2047 | West Chicago | USA | Right | Left | 6' 2" | 200 lbs | - |
| Sweeney, Donnie | RF | Sacramento River Cats | 25 | 11/10/2045 | Austin | USA | Left | Left | 6' 4" | 215 lbs | - |
| Sánchez, Emílio | 2B | Reno Aces | 29 | 05/20/2042 | Cabimas | VEN | Right | Right | 6' 1" | 200 lbs | - |
| Sánchez, José | RP | Free Agent | 28 | 08/13/2042 | Springdale | USA | Right | Right | 5' 11" | 165 lbs | - |
| Sánchez, Juan | SS | New Orleans Zephyrs | 24 | 02/26/2047 | Los Angeles | USA | Left | Right | 6' 2" | 190 lbs | - |
