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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sadoval, Luis | CF | Cedar Rapids Kernels | 23 | 03/17/2019 | Guatire | VEN | Right | Right | 6' 0" | 185 lbs | - |
| Salas, António | C | Great Lakes Loons | 21 | 05/11/2021 | Long View | USA | Right | Right | 6' 2" | 200 lbs | - |
| Salazar, Arturo | RP | Lake County Captains | 23 | 12/17/2018 | Santo Domingo | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Salcido, Jesús | SS | Quad Cities River Bandits | 21 | 09/03/2020 | Kettering | USA | Switch | Right | 6' 4" | 190 lbs | - |
| Sampson, Jim | SP | Great Lakes Loons | 22 | 07/01/2019 | Grove City | USA | Right | Right | 6' 4" | 185 lbs | - |
| Sanders, Bubba | CF | Free Agent | 23 | 12/06/2018 | Sayreville | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sanders, Ron | C | Free Agent | 26 | 05/13/2016 | Centreville | USA | Switch | Right | 5' 11" | 195 lbs | - |
| Sanders, Vern | RP | Free Agent | 31 | 09/06/2010 | Glendora | USA | Left | Left | 6' 4" | 200 lbs | - |
| Santos, Arturo | 1B | Peoria Chiefs | 23 | 11/06/2018 | Honolulu | USA | Right | Right | 6' 2" | 190 lbs | - |
| Schmitt, Andy | SP | Fort Wayne TinCaps | 22 | 10/17/2019 | Wichita | USA | Left | Right | 5' 10" | 180 lbs | - |
| Schmitt, Shawn | LF | South Bend Cubs | 21 | 11/17/2020 | Ewing | USA | Left | Left | 6' 6" | 190 lbs | - |
| Schneider, Ben | LF | Beloit Snappers | 22 | 07/22/2019 | Winston-Salem | USA | Right | Right | 6' 0" | 185 lbs | - |
| Scott, Dave | CF | South Bend Cubs | 22 | 01/31/2020 | Tulsa | USA | Right | Right | 5' 11" | 160 lbs | - |
| Scott, Eric | SP | Quad Cities River Bandits | 32 | 02/10/2010 | Roseville | USA | Right | Right | 6' 8" | 200 lbs | - |
| Scott, Tim | SS | Peoria Chiefs | 28 | 07/20/2013 | New Orleans | USA | Switch | Right | 6' 0" | 190 lbs | - |
| Serrano, Rubén | C | Cedar Rapids Kernels | 23 | 02/03/2019 | Santo Domingo | DOM | Right | Right | 6' 2" | 205 lbs | - |
| Serrano, Tomás | CF | Beloit Snappers | 22 | 10/20/2019 | Coamo | PUR | Right | Right | 6' 3" | 195 lbs | - |
| Shannon, Steve | CF | Great Lakes Loons | 22 | 05/05/2020 | Ashland | USA | Left | Right | 6' 5" | 200 lbs | - |
| Shields, Steve | SP | West Michigan Whitecaps | 23 | 08/25/2018 | Danbury | USA | Left | Left | 6' 4" | 200 lbs | - |
| Shields, Ted | CF | Dayton Dragons | 23 | 11/26/2018 | Minneapolis | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sierra, Raúl | C | Cedar Rapids Kernels | 24 | 12/24/2017 | East Orange | USA | Right | Right | 6' 0" | 205 lbs | - |
| Silva, Luis | SP | Cedar Rapids Kernels | 22 | 11/01/2019 | Managua | NCA | Right | Left | 6' 9" | 200 lbs | - |
| Sizemore, Steve | 3B | Free Agent | 25 | 08/06/2016 | Columbia | USA | Right | Right | 5' 10" | 185 lbs | - |
| Smith, Ben | 1B | Lake County Captains | 24 | 09/01/2017 | Newark | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Bob | 3B | Lake County Captains | 23 | 03/28/2019 | Memphis | USA | Right | Right | 6' 1" | 190 lbs | - |
| Smith, Brad | 3B | Great Lakes Loons | 24 | 10/17/2017 | Lathrop | USA | Switch | Right | 5' 10" | 190 lbs | - |
| Smith, Dave | RF | Wisconsin Timber Rattlers | 23 | 09/07/2018 | Watervliet | USA | Right | Left | 6' 4" | 195 lbs | - |
| Smith, Jimmy | RF | Lansing Lugnuts | 28 | 04/06/2014 | San Francisco | USA | Left | Left | 6' 1" | 195 lbs | - |
| Smith, Randy | RP | South Bend Cubs | 28 | 12/29/2013 | Biddeford | USA | Right | Right | 6' 0" | 200 lbs | - |
| Snelling, Mike | CF | Free Agent | 28 | 01/19/2014 | Charleston | USA | Right | Right | 6' 4" | 205 lbs | - |
| Snyder, Tim | 1B | Free Agent | 33 | 01/14/2009 | Springfield | USA | Right | Right | 6' 6" | 205 lbs | - |
| Solís, Luis | C | Wisconsin Timber Rattlers | 20 | 11/20/2021 | Santo Domingo | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Solís, Raúl | SP | Lansing Lugnuts | 21 | 09/28/2020 | Villa Los Almacigos | DOM | Right | Right | 6' 0" | 165 lbs | - |
| Souza, Cisco | RP | Free Agent | 25 | 09/30/2016 | Mao | DOM | Right | Right | 5' 11" | 180 lbs | - |
| St. John, Danny | SP | Lake County Captains | 21 | 04/15/2021 | Westfield Center | USA | Right | Right | 6' 0" | 170 lbs | - |
| Stewart, Ron | SP | Wisconsin Timber Rattlers | 24 | 09/21/2017 | Westmont | USA | Switch | Right | 6' 4" | 200 lbs | $750,000 |
| Stone, Dave | 1B | Quad Cities River Bandits | 22 | 11/22/2019 | Los Angeles | USA | Right | Right | 6' 3" | 215 lbs | - |
| Stover, Curt | CF | Fort Wayne TinCaps | 26 | 03/22/2016 | Highland Heights | USA | Left | Right | 6' 4" | 205 lbs | - |
| Stratford, Dave | RF | West Michigan Whitecaps | 25 | 05/11/2017 | Bayside | USA | Right | Left | 6' 3" | 200 lbs | - |
| Sánchez, Ignacio | LF | Free Agent | 24 | 03/02/2018 | Santo Domingo | DOM | Right | Left | 6' 1" | 190 lbs | - |
| Sánchez, Juan | RP | Peoria Chiefs | 24 | 08/10/2017 | Miches | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, Juan | C | Fort Wayne TinCaps | 22 | 05/21/2020 | Santo Domingo | DOM | Right | Right | 6' 3" | 205 lbs | - |
| Sánchez, Tony | SS | Beloit Snappers | 23 | 02/06/2019 | Barcelona | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Sørensen, Greg | 3B | Great Lakes Loons | 24 | 06/20/2018 | Charlotte | USA | Right | Right | 6' 2" | 190 lbs | - |
