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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Riley O'Brien | 2019-2023 | .000 | 0 | 0 | 16 | 24 | 3 | 4.27 | 396 |
| Darren O'Day | 2021-2021 | .000 | 0 | 0 | 3 | 3 | 5 | 3.96 | 41 |
| Logan O'Hoppe | 2022-2023 | .271 | 14 | 60 | 0 | 0 | 0 | 0.00 | 0 |
| Brian O'Keefe | 2023-2023 | .272 | 4 | 20 | 0 | 0 | 0 | 0.00 | 0 |
| Jack O'Loughlin | 2021-2021 | .000 | 0 | 0 | 0 | 1 | 0 | 14.73 | 2 |
| Tyler O'Neill | 2019-2021 | .236 | 36 | 118 | 0 | 0 | 0 | 3.00 | 2 |
| Trevor Oaks | 2019-2021 | .000 | 0 | 0 | 6 | 6 | 1 | 3.56 | 123 |
| Bailey Ober | 2021-2023 | .000 | 0 | 0 | 10 | 7 | 3 | 3.48 | 156 |
| Scott Oberg | 2021-2023 | .000 | 0 | 0 | 1 | 2 | 6 | 1.36 | 25 |
| Josh Ockimey | 2019-2022 | .270 | 3 | 16 | 0 | 0 | 0 | 0.00 | 0 |
| Rougned Odor | 2021-2023 | .249 | 27 | 98 | 0 | 0 | 0 | 0.00 | 0 |
| Jake Odorizzi | 2019-2023 | .000 | 0 | 0 | 9 | 9 | 0 | 5.01 | 119 |
| Shohei Ohtani | 2019-2019 | .700 | 1 | 3 | 1 | 0 | 0 | 1.50 | 2 |
| Steven Okert | 2022-2022 | .000 | 0 | 0 | 0 | 0 | 0 | 14.73 | 4 |
| Chris Okey | 2021-2021 | .064 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Jon Olczak | 2020-2022 | .000 | 0 | 0 | 0 | 6 | 8 | 4.00 | 92 |
| Edward Olivares | 2019-2023 | .254 | 13 | 82 | 0 | 0 | 0 | 0.00 | 0 |
| Helcris Olivarez | 2023-2023 | .000 | 0 | 0 | 0 | 0 | 0 | 5.40 | 2 |
| Jorge Ona | 2021-2023 | .232 | 22 | 70 | 0 | 0 | 0 | 0.00 | 0 |
| Demi Orimoloye | 2021-2023 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Rafael Ortega | 2023-2023 | .316 | 9 | 46 | 0 | 0 | 0 | 0.00 | 0 |
| Joey Ortiz | 2022-2022 | .211 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Luis Ortiz | 2019-2022 | .000 | 0 | 0 | 27 | 23 | 2 | 3.47 | 436 |
| Robinson Ortiz | 2022-2022 | .000 | 0 | 0 | 0 | 1 | 0 | 3.00 | 0 |
| Eric Orze | 2023-2023 | .000 | 0 | 0 | 1 | 0 | 0 | 4.91 | 26 |
| Josh Osich | 2020-2023 | .000 | 0 | 0 | 10 | 6 | 3 | 2.73 | 180 |
| Roberto Osuna | 2019-2020 | .000 | 0 | 0 | 0 | 0 | 1 | 1.93 | 7 |
| Corey Oswalt | 2021-2023 | .000 | 0 | 0 | 6 | 10 | 0 | 4.27 | 142 |
| Andy Otero | 2023-2023 | .000 | 0 | 0 | 2 | 2 | 1 | 4.89 | 32 |
| Adam Ottavino | 2020-2022 | .000 | 0 | 0 | 5 | 2 | 2 | 3.74 | 95 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Glenn Otto | 2019-2023 | .000 | 0 | 0 | 14 | 5 | 9 | 3.32 | 108 |
| James Outman | 2023-2023 | .174 | 4 | 21 | 0 | 0 | 0 | 0.00 | 0 |
| Connor Overton | 2023-2023 | .000 | 0 | 0 | 9 | 7 | 0 | 3.49 | 92 |
| Luis Oviedo | 2020-2023 | .000 | 0 | 0 | 11 | 6 | 9 | 3.98 | 186 |
| Chris Owings | 2019-2019 | .217 | 3 | 18 | 0 | 0 | 0 | 0.00 | 0 |
| Marcell Ozuna | 2023-2023 | .242 | 6 | 19 | 0 | 0 | 0 | 0.00 | 0 |
