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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saladin, Darlin | SP | Los Angeles A (AZL) Angels | 21 | 12/28/2002 | San Pedro de Macorís | DOM | Right | Right | 5' 11" | 145 lbs | - |
| Salgado, Bryant | RP | Baltimore (GCL) Orioles | 24 | 03/02/2000 | Houston | USA | Right | Right | 5' 11" | 205 lbs | - |
| Saltiban, Devin | CF | Phoenix Seafarers | 19 | 02/14/2005 | Hilo | USA | Right | Right | 5' 9" | 175 lbs | - |
| Salvador, Andricson | RP | Free Agent | 23 | 07/24/2000 | Puerto Plata | DOM | Left | Left | 5' 11" | 185 lbs | - |
| Sanchez, Carlos | 3B | San Antonio Ramblers | 19 | 01/12/2005 | Santo Domingo | DOM | Left | Right | 6' 0" | 180 lbs | - |
| Sanchez, Yehizon | SP | Free Agent | 23 | 11/16/2000 | La Romana | DOM | Right | Right | 6' 2" | 170 lbs | - |
| Santana, Adrian | SS | Detroit (GCL) Tigers | 18 | 07/18/2005 | Miami | USA | Switch | Right | 6' 0" | 165 lbs | - |
| Santana, Ruben | 3B | Toronto (GCL) Blue Pirates | 19 | 02/16/2005 | El Seibo | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Santana, Welington | RF | Free Agent | 23 | 05/20/2001 | Unknown | VIR | Right | Right | 6' 3" | 190 lbs | - |
| Santana, Yohanfer | SP | New York A (GCL) Yankees | 18 | 10/13/2005 | San Pedro de Macorís | DOM | Right | Right | 6' 7" | 205 lbs | - |
| Santander, Juan | 1B | San Francisco (AZL) Giants | 21 | 12/09/2002 | Barquisimeto | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Santos, Nolan | SP | Philadelphia (GCL) Phillies | 23 | 12/07/2000 | Miami Beach | USA | Right | Right | 6' 1" | 180 lbs | - |
| Santos, Rael | RP | Free Agent | 23 | 03/29/2001 | San Francisco de Macorís | DOM | Right | Right | 6' 3" | 165 lbs | - |
| Savage, Luke | RP | Free Agent | 22 | 08/10/2001 | Dallas | USA | Right | Right | 6' 1" | 200 lbs | - |
| Savino, Nate | SP | Detroit (GCL) Tigers | 22 | 01/24/2002 | Sterling | USA | Left | Left | 6' 3" | 215 lbs | - |
| Sayre, Alec | RF | Free Agent | 23 | 10/05/2000 | Dover | USA | Right | Right | 6' 0" | 195 lbs | - |
| Scarborough, Caden | RP | San Antonio Ramblers | 19 | 04/01/2005 | St. Cloud | USA | Right | Right | 6' 5" | 185 lbs | - |
| Schlaffer, Tyler | SP | Free Agent | 23 | 05/24/2001 | Homewood | USA | Right | Right | 6' 1" | 185 lbs | - |
| Schoenwetter, Cole | CL | Houston (AZL) Astros | 19 | 10/01/2004 | Santa Barbara | USA | Right | Right | 6' 3" | 190 lbs | - |
| Schofield-Sam, T.J. | 3B | Baltimore (GCL) Orioles | 22 | 06/20/2001 | Brampton | CAN | Left | Right | 6' 1" | 190 lbs | - |
| Schultz, Noah | SP | San Diego (AZL) Padres 1 | 20 | 08/05/2003 | Aurora | USA | Left | Left | 6' 9" | 220 lbs | - |
| Seijas, Rothaikeg | CF | New York N (GCL) Mets | 21 | 07/22/2002 | San Felipe | VEN | Right | Right | 5' 11" | 170 lbs | - |
| Semerite, Moises | SS | New York A (GCL) Yankees | 18 | 05/31/2006 | Azua | DOM | Right | Right | 6' 0" | 150 lbs | - |
| Serna, Luis | SP | San Diego (AZL) Padres 1 | 19 | 07/20/2004 | San Luis Río Colorado | MEX | Right | Right | 5' 11" | 145 lbs | - |
| Serrano, Florencio | SP | Free Agent | 24 | 02/23/2000 | Corpus Christi | USA | Right | Right | 6' 2" | 210 lbs | - |
| Serrano, Jhoniel | RP | New York N (GCL) Mets | 20 | 10/17/2003 | Unknown | VEN | Right | Right | 6' 0" | 180 lbs | - |
| Shade, Colby | CF | San Francisco (AZL) Giants | 22 | 08/18/2001 | Windsor | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sharkey, Teddy | RP | San Francisco (AZL) Giants | 22 | 08/01/2001 | Unknown | USA | Right | Right | 5' 11" | 200 lbs | - |
| Silva, Carlos | C | Boston (GCL) Red Sox | 18 | 03/01/2006 | El Tigre | VEN | Right | Right | 5' 10" | 170 lbs | - |
| Silvera, Andres | SP | Miami (GCL) Marlins | 19 | 07/20/2004 | David | PAN | Right | Right | 6' 0" | 190 lbs | - |
| Simon, Ben | RP | Los Angeles A (AZL) Angels | 22 | 03/22/2002 | Hightstown | USA | Left | Right | 5' 11" | 200 lbs | - |
| Simon, Liam | SP | Texas (AZL) Rangers | 23 | 10/16/2000 | Princeton | USA | Right | Right | 6' 4" | 215 lbs | - |
| Simpson, Will | 1B | Boston (GCL) Red Sox | 22 | 08/28/2001 | Sammamish | USA | Right | Right | 6' 4" | 210 lbs | - |
| Skipper, Carson | RP | Atlanta (GCL) Braves | 24 | 08/12/1999 | Trussville | USA | Left | Left | 6' 3" | 205 lbs | - |
| Smith, Aidan | CF | Texas (AZL) Rangers | 19 | 07/23/2004 | Lucas | USA | Right | Right | 6' 3" | 190 lbs | - |
| Smith, Brady | SP | Flower Mound Air Riders | 19 | 01/27/2005 | Bean Station | USA | Right | Right | 6' 2" | 170 lbs | - |
| Smith, David | CF | Miami (GCL) Marlins | 23 | 02/20/2001 | Collegeville | USA | Switch | Right | 5' 11" | 185 lbs | - |
| Smith, Dylan | RP | Seattle (AZL) Mariners | 24 | 05/28/2000 | Stafford | USA | Right | Right | 6' 2" | 180 lbs | - |
| Smith, Jake | RP | Washington (GCL) Nationals | 24 | 10/04/1999 | Chapel Hill | USA | Right | Right | 6' 4" | 190 lbs | - |
| Snell, Ryan | C | Philadelphia (GCL) Phillies | 24 | 04/14/2000 | Beaumont | USA | Right | Right | 5' 10" | 205 lbs | - |
| Sojo, Alberto | CL | Chicago N (AZL) Cubs | 23 | 09/23/2000 | Unknown | VEN | Right | Right | 5' 11" | 165 lbs | - |
| Solano, Yoffry | 2B | Atlanta (GCL) Braves | 19 | 11/04/2004 | Nizao | DOM | Switch | Right | 5' 11" | 180 lbs | - |
| Sosa, Gabriel | RP | Chicago N (AZL) Cubs | 23 | 04/17/2001 | Unknown | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Soto, Charlee | SP | Detroit (GCL) Tigers | 18 | 08/31/2005 | Kissimmee | USA | Switch | Right | 6' 5" | 210 lbs | - |
| Soto, Elvis | RP | Philadelphia (GCL) Phillies | 20 | 03/02/2004 | Unknown | DOM | Right | Right | 6' 0" | 175 lbs | - |
| Soto, Franklin | 2B | Baltimore (GCL) Orioles | 24 | 09/23/1999 | San Cristóbal | DOM | Right | Right | 5' 11" | 175 lbs | - |
| Specht, Tommy | CF | Los Angeles N (AZL) Dodgers | 19 | 06/24/2004 | Dubuque | USA | Left | Right | 6' 2" | 195 lbs | - |
| Stafura, Sammy | 2B | Atlanta (GCL) Braves | 19 | 11/15/2004 | Lake Mohegan | USA | Right | Right | 6' 1" | 190 lbs | - |
| Stanley, Max | SP | New York N (GCL) Mets | 19 | 11/20/2004 | Parker | USA | Left | Right | 6' 3" | 170 lbs | - |
| Starks, Gabriel | RP | Houston (AZL) Astros | 22 | 12/26/2001 | Pine Bluff | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stevens, Felix | LF | Free Agent | 24 | 07/30/1999 | Havana | CUB | Right | Right | 6' 4" | 230 lbs | - |
| Stevens, Will | RP | Texas (AZL) Rangers | 22 | 07/18/2001 | Kansas City | USA | Right | Right | 6' 3" | 220 lbs | - |
| Stoffal, Jace | SP | Jacksonville Revolution | 21 | 07/19/2002 | Roseburg | USA | Right | Right | 6' 3" | 220 lbs | - |
| Stupp, Cole | RP | Phoenix Seafarers | 23 | 11/10/2000 | Alpharetta | USA | Right | Right | 6' 4" | 205 lbs | - |
| Suarez, Santiago | SP | Houston (AZL) Astros | 19 | 01/11/2005 | Cumana | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Sullivan, Sean | SP | Philadelphia (GCL) Phillies | 21 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
| Sullivan, Sean | RP | Jacksonville Revolution | 23 | 10/02/2000 | Los Angeles | USA | Right | Right | 6' 1" | 175 lbs | - |
| Sullivan, William | LF | Boston (GCL) Red Sox | 23 | 11/25/2000 | Norland | USA | Left | Right | 6' 4" | 205 lbs | - |
| Surumuy, Jeicol | SP | Toronto (GCL) Blue Pirates | 18 | 01/09/2006 | Maracaibo | VEN | Right | Right | 6' 3" | 180 lbs | - |
| Sykora, Travis | SP | New York N (GCL) Mets | 20 | 04/28/2004 | Round Rock | USA | Right | Right | 6' 6" | 215 lbs | - |
