| # | Name | Team | Opp | Date | Score | IP | R | H | HR | BB | K | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Luis Castillo | NYM | MIA | April 11, 2025 | 4-0 | 9.0 | 0 | 4 | 0 | 0 | 13 | 99 |
| 2 | Ryan Pepiot | LAA | SEA | April 26, 2025 | 2-0 | 8.0 | 0 | 1 | 0 | 0 | 9 | 95 |
| 3 | George Kirby | BOS | TOR | April 9, 2025 | 7-0 | 9.0 | 0 | 3 | 0 | 1 | 9 | 95 |
| 4 | Bobby Miller | TEX | SD | May 9, 2025 | 3-0 | 8.0 | 0 | 1 | 0 | 1 | 8 | 92 |
| 5 | Yoshinobu Yamamoto | MIL | PHI | May 8, 2025 | 8-0 | 8.1 | 0 | 5 | 0 | 0 | 12 | 92 |
| 6 | Brandon Woodruff | SF | COL | May 4, 2025 | 10-0 | 9.0 | 0 | 4 | 0 | 0 | 5 | 91 |
| 7 | Eury Perez | SF | LAD | April 1, 2025 | 3-0 | 8.0 | 0 | 4 | 0 | 0 | 11 | 91 |
| 8 | Shane McClanahan | DET | CHC | April 16, 2025 | 5-1 | 8.0 | 1 | 1 | 0 | 0 | 8 | 91 |
| 9 | Paul Skenes | MIN | WAS | April 23, 2025 | 5-1 | 9.0 | 0 | 4 | 0 | 2 | 9 | 91 |
| 10 | Paul Skenes | MIN | TEX | March 29, 2025 | 2-1 | 7.1 | 0 | 4 | 0 | 0 | 14 | 90 |
| 11 | Paul Skenes | MIN | STL | May 20, 2025 | 8-0 | 8.0 | 0 | 4 | 0 | 0 | 10 | 90 |
| 12 | Luis Castillo | NYM | PIT | June 10, 2025 | 6-0 | 9.0 | 0 | 4 | 0 | 2 | 7 | 89 |
| 13 | Carlos Rodon | DET | SEA | June 4, 2025 | 5-1 | 8.0 | 0 | 2 | 0 | 2 | 8 | 88 |
| 14 | Reese Olson | MIN | LAD | April 12, 2025 | 2-0 | 8.0 | 0 | 2 | 0 | 1 | 6 | 88 |
| 15 | Zach Eflin | LAA | BAL | April 29, 2025 | 9-0 | 8.0 | 0 | 2 | 0 | 1 | 6 | 88 |
| 16 | Nick Pivetta | STL | LAA | May 18, 2025 | 11-2 | 7.0 | 0 | 1 | 0 | 1 | 10 | 88 |
| 17 | Reid Detmers | NYY | CHC | June 6, 2025 | 9-0 | 7.2 | 0 | 2 | 0 | 1 | 8 | 88 |
| 18 | Logan Gilbert | NYM | WAS | June 1, 2025 | 1-0 | 7.1 | 0 | 3 | 0 | 0 | 10 | 88 |
| 19 | Paul Skenes | MIN | STL | May 4, 2025 | 2-3 | 8.0 | 0 | 3 | 0 | 2 | 10 | 88 |
| 20 | Joe Ryan | LAA | SD | April 5, 2025 | 7-0 | 7.1 | 0 | 2 | 0 | 2 | 11 | 87 |
| 21 | Dylan Cease | BOS | NYM | June 9, 2025 | 5-0 | 7.0 | 0 | 1 | 0 | 2 | 10 | 86 |
| 22 | Reynaldo Lopez | ATL | NYY | June 5, 2025 | 3-0 | 8.0 | 0 | 3 | 0 | 1 | 5 | 85 |
| 23 | Joe Ryan | LAA | LAD | April 17, 2025 | 0-1 | 8.0 | 1 | 2 | 0 | 2 | 8 | 85 |
| 24 | Jack Flaherty | STL | DET | March 29, 2025 | 4-0 | 7.0 | 0 | 1 | 0 | 3 | 10 | 84 |
| 25 | David Peterson | PIT | HOU | May 19, 2025 | 9-1 | 8.0 | 0 | 3 | 0 | 1 | 3 | 83 |
| 26 | Shane Bieber | ATL | SD | June 9, 2025 | 1-0 | 7.1 | 0 | 2 | 0 | 3 | 9 | 83 |
| 27 | Dustin May | LAD | BOS | May 6, 2025 | 3-1 | 7.1 | 0 | 4 | 0 | 1 | 9 | 83 |
| 28 | MacKenzie Gore | SD | ATL | June 9, 2025 | 0-1 | 8.2 | 1 | 3 | 1 | 0 | 6 | 83 |
| 29 | Ian Anderson | STL | HOU | May 15, 2025 | 2-1 | 7.1 | 0 | 2 | 0 | 1 | 5 | 83 |
| 30 | Blake Snell | TEX | NYY | May 21, 2025 | 10-0 | 7.0 | 0 | 3 | 0 | 1 | 9 | 83 |